SCHEMBL8634858

SCHEMBL8634858

CC(C)Oc1ccc(Oc2ccc(OCC=C(Cl)Cl)cc2C(C)C)cc1

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.39
THRB P10828 1/20 0.37
RORC P51449 1/20 0.37
ACACB O00763 2/20 0.34
ACACA Q13085 1/20 0.34
P2RX3 P56373 1/20 0.34
P2RX2 Q9UBL9 1/20 0.34
HTR2A P28223 1/20 0.34
SLC6A4 P31645 1/20 0.34
KCNH2 Q12809 1/20 0.34
PTGDR Q13258 1/20 0.33
POLB P06746 1/20 0.32
ALDH1A3 P47895 1/20 0.32
FFAR4 Q5NUL3 6/20 0.31
KMT2A Q03164 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8635966 0.90 THRB (0.39) HTTTHRBRORCACACBACACA
SCHEMBL8633420 0.89 MAPT (0.42) HTTTHRBRORCACACBACACA
SCHEMBL8635790 0.88 PTGDR (0.37) HTTTHRBRORCACACBACACA
SCHEMBL8635792 0.86 THRB (0.35) HTTTHRBRORCACACBACACA
SCHEMBL8633931 0.86 HTT (0.39) HTTACACBACACAPTGDRFFAR4
SCHEMBL8635158 0.84 HTT (0.40) HTTACACBACACAHTR2ASLC6A4
SCHEMBL8636900 0.81 THRB (0.39) HTTTHRBRORCHTR2ASLC6A4
SCHEMBL8635806 0.81 ACACB (0.36) HTTTHRBRORCACACBACACA
SCHEMBL8633877 0.80 THRB (0.39) HTTTHRBRORCP2RX3P2RX2
SCHEMBL8638478 0.80 ACACB (0.35) HTTTHRBRORCACACBACACA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648729-B1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL CO (JP) 1998-07-15 EP disclosed
US-5698702-A INTERMEDIATES FOR INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-12-16 US disclosed
US-5530015-A Dihaloprene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient, and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-06-25 US disclosed
EP-0648729-A1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-04-19 EP disclosed