SCHEMBL8635792

SCHEMBL8635792

CC(C)Oc1ccc(Oc2ccc(Oc3ccccc3OCC=C(Cl)Cl)c(C(C)C)c2)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.35
RORC P51449 2/20 0.35
PTGDR Q13258 1/20 0.34
ACACB O00763 1/20 0.33
ACACA Q13085 1/20 0.33
P2RX3 P56373 1/20 0.33
P2RX2 Q9UBL9 1/20 0.33
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
CASP1 P29466 1/20 0.32
PNLIP P16233 1/20 0.32
HTT P42858 1/20 0.32
MCL1 Q07820 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
OPRM1 P35372 1/20 0.31
OPRD1 P41143 1/20 0.31
SLC6A4 P31645 4/20 0.31
HTR2A P28223 2/20 0.31
KCNH2 Q12809 2/20 0.31
SLC6A2 P23975 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8635790 0.93 PTGDR (0.37) THRBRORCPTGDRACACBACACA
SCHEMBL8635966 0.91 THRB (0.39) THRBRORCPTGDRACACBACACA
SCHEMBL8631883 0.89 PTGDR (0.34) THRBRORCPTGDRACACBACACA
SCHEMBL8634858 0.86 HTT (0.39) THRBRORCPTGDRACACBACACA
SCHEMBL8635018 0.85 THRB (0.40) THRBRORCMEN1KMT2AHTT
SCHEMBL8636137 0.83 ACACB (0.36) PTGDRACACBACACAMEN1KMT2A
SCHEMBL8631880 0.82 PTGDR (0.37) THRBRORCPTGDRACACBACACA
SCHEMBL8635806 0.82 ACACB (0.36) THRBRORCPTGDRACACBACACA
SCHEMBL8638478 0.81 ACACB (0.35) THRBRORCPTGDRACACBACACA
SCHEMBL8632130 0.81 FFAR4 (0.40) PTGDRACACBACACAMCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648729-B1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL CO (JP) 1998-07-15 EP disclosed
US-5698702-A INTERMEDIATES FOR INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-12-16 US disclosed
US-5530015-A Dihaloprene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient, and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-06-25 US disclosed
EP-0648729-A1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-04-19 EP disclosed