Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.43 |
| ▸ | HRH1 | P35367 | 4/20 | 0.42 |
| ▸ | HRH2 | P25021 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | TGM2 | P21980 | 1/20 | 0.37 |
| ▸ | ME2 | P23368 | 1/20 | 0.37 |
| ▸ | ME1 | P48163 | 1/20 | 0.37 |
| ▸ | ME3 | Q16798 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9079714 | 0.83 | ITGB3 (0.69) | ITGB3ITGA2BHRH3HRH1HRH2 | |
| SCHEMBL7332630 | 0.82 | ITGB3 (0.59) | ITGB3ITGA2BHRH3HRH1SMN1; SMN2 | |
| SCHEMBL8696504 | 0.80 | HRH3 (0.51) | ITGB3ITGA2BHRH3HRH1HRH2 | |
| SCHEMBL8635829 | 0.77 | MAPT (0.57) | ITGB3ITGA2BHRH3HRH1HRH2 | |
| SCHEMBL7398342 | 0.76 | ITGB3 (0.49) | ITGB3ITGA2BHRH3HRH1SMN1; SMN2 | |
| SCHEMBL8634727 | 0.76 | HRH3 (0.55) | ITGB3ITGA2BHRH3HRH1HRH2 | |
| Hydrochloric Acid SCHEMBL8681087 | 0.76 | MAPT (0.56) | ITGB3ITGA2BHRH3HRH1HRH2 | |
| SCHEMBL7407497 | 0.76 | SMN1; SMN2 (0.47) | ITGB3ITGA2BSMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL8837938 | 0.72 | CHKA (0.47) | ITGB3ITGA2BHRH3SMN1; SMN2CYP2C9 | |
| SCHEMBL8837943 | 0.71 | ITGB3 (0.48) | ITGB3ITGA2BHRH3HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5728701-A | INHIBIT PLATELET AGGREGATION | ZENECA LIMITED (GB) | 1998-03-17 | — | — | US | claimed |
| US-5753659-A | ANTICOAGULANTS FOR BLOOD DISORDER, CARDIOVASCULAR DISORDER, THROMBOSIS, | ZENECA LIMITED (GB) | 1998-05-19 | — | — | US | disclosed |
| US-5750754-A | TERTIARY BUTYL 3-METHYL-4-SUBSTITUTED BUTYRATE; CHEMICAL INTERMEDIATES FOR ANTICAOGULANT DRUGS | ZENECA LIMITED (GB) | 1998-05-12 | — | — | US | disclosed |