Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.56 |
| ▸ | HRH1 | P35367 | 5/20 | 0.56 |
| ▸ | HRH2 | P25021 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8681087 | 0.99 | MAPT (0.56) | MAPTNPC1RAB9ASMN1; SMN2HRH3 | |
| SCHEMBL8634727 | 0.96 | HRH3 (0.55) | MAPTNPC1RAB9ASMN1; SMN2HRH3 | |
| SCHEMBL8696504 | 0.86 | HRH3 (0.51) | MAPTNPC1RAB9ASMN1; SMN2HRH3 | |
| Hydrochloric Acid SCHEMBL8837971 | 0.80 | HRH3 (0.44) | HRH3TSHRMAPK1ALDH1A1GAA | |
| SCHEMBL8637100 | 0.80 | HRH3 (0.44) | MAPTHRH3LMNATSHRALDH1A1 | |
| SCHEMBL7334548 | 0.80 | ITGB3 (0.62) | MAPTNPC1RAB9ASMN1; SMN2HRH3 | |
| SCHEMBL8635008 | 0.78 | ITGB3 (0.44) | SMN1; SMN2HRH3TSHRALDH1A1GAA | |
| SCHEMBL7398027 | 0.78 | MAPT (0.56) | MAPTNPC1RAB9ASMN1; SMN2HRH3 | |
| SCHEMBL8837938 | 0.78 | CHKA (0.47) | SMN1; SMN2HRH3TSHRALDH1A1GAA | |
| SCHEMBL6482397 | 0.77 | MAPT (0.54) | MAPTNPC1RAB9ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753659-A | ANTICOAGULANTS FOR BLOOD DISORDER, CARDIOVASCULAR DISORDER, THROMBOSIS, | ZENECA LIMITED (GB) | 1998-05-19 | — | — | US | disclosed |
| US-5750754-A | TERTIARY BUTYL 3-METHYL-4-SUBSTITUTED BUTYRATE; CHEMICAL INTERMEDIATES FOR ANTICAOGULANT DRUGS | ZENECA LIMITED (GB) | 1998-05-12 | — | — | US | disclosed |