Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 16/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 4/20 | 0.40 |
| ▸ | HRH2 | P25021 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7403779 | 0.90 | ITGB3 (0.58) | ITGB3ITGA2BHRH3HRH1HRH2 | |
| SCHEMBL7335391 | 0.82 | HRH3 (0.50) | ITGB3ITGA2BHRH3KCNH2MAPT | |
| SCHEMBL7333032 | 0.80 | HRH3 (0.47) | ITGB3ITGA2BHRH3KCNH2MAPT | |
| SCHEMBL7994992 | 0.78 | LMNA (0.43) | MAPK1 | |
| SCHEMBL7332462 | 0.76 | GRM5 (0.47) | ITGB3ITGA2BHRH3KCNH2MAPT | |
| SCHEMBL8634522 | 0.74 | HRH3 (0.47) | ITGB3ITGA2BHRH3KCNH2MAPT | |
| SCHEMBL7324874 | 0.71 | CHKA (0.41) | KCNH2MAPTPKM | |
| SCHEMBL9081854 | 0.71 | ITGB3 (0.51) | ITGB3ITGA2BHRH3MAPTPKM | |
| SCHEMBL9080518 | 0.69 | ITGB3 (0.54) | ITGB3ITGA2BHRH3HRH1HRH2 | |
| SCHEMBL7393253 | 0.69 | ITGB3 (0.56) | ITGB3ITGA2BHRH3MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691959-B1 | HETEROCYCLIC DERIVATIVES AS PLATELET AGGREGATION INHIBITORS | ZENECA LTD (GB) | 1998-07-22 | — | — | EP | claimed |