Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | USP8 | P40818 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8629853 | 0.91 | MEN1 (0.45) | CA12CA2CA9CA1MEN1 | |
| SCHEMBL8630569 | 0.89 | MEN1 (0.43) | CA12CA2CA9CA1MEN1 | |
| SCHEMBL8635015 | 0.89 | KDM1A (0.45) | MEN1KMT2ALMNAMAPTKDM4E | |
| SCHEMBL8629976 | 0.82 | L3MBTL1 (0.51) | MEN1KMT2ALMNAMAPTKDM4E | |
| SCHEMBL8631355 | 0.80 | L3MBTL1 (0.44) | MEN1KMT2AMAPTKDM4EHSD11B1 | |
| SCHEMBL8632682 | 0.79 | KDM1A (0.46) | MEN1KMT2ALMNAMAPTKDM4E | |
| SCHEMBL8633591 | 0.79 | L3MBTL1 (0.43) | MEN1KMT2ALMNAMAPTKDM4E | |
| SCHEMBL8632831 | 0.79 | KMT2A (0.44) | CA12CA2CA9CA1MEN1 | |
| SCHEMBL8635392 | 0.79 | L3MBTL1 (0.49) | CA12CA2CA9CA1KMT2A | |
| SCHEMBL8630886 | 0.79 | MCL1 (0.45) | MEN1KMT2ATDP1MCL1HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |