SCHEMBL8635199

SCHEMBL8635199

Cc1c(C(=O)O)ccc2c1C(=O)c1ccccc1C2=O

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.66
ALDH1A1 P00352 5/20 0.66
MAPK1 P28482 4/20 0.66
MEN1 O00255 3/20 0.66
KMT2A Q03164 3/20 0.66
LMNA P02545 2/20 0.66
POLB P06746 2/20 0.66
THRB P10828 1/20 0.66
RECQL P46063 1/20 0.66
SMN1; SMN2 Q16637 3/20 0.65
KDM4E B2RXH2 1/20 0.65
MMP14 P50281 1/20 0.65
L3MBTL1 Q9Y468 2/20 0.64
PKM P14618 1/20 0.60
TTR P02766 3/20 0.59
TSHR P16473 2/20 0.55
CYP1A2 P05177 1/20 0.55
CYP2D6 P10635 1/20 0.55
CYP2C9 P11712 1/20 0.55
CYP2C19 P33261 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28318060 0.82 MAPT (0.73) MAPTALDH1A1MAPK1MEN1KMT2A
SCHEMBL68628 0.81 MAPT (0.68) MAPTALDH1A1MAPK1MEN1KMT2A
SCHEMBL11411791 0.81 FTO (0.73) MAPTALDH1A1MAPK1MEN1KMT2A
SCHEMBL27880004 0.80 ADORA2A (0.65) MAPTALDH1A1MAPK1MEN1KMT2A
SCHEMBL3453760 0.79 MAPT (0.66) MAPTALDH1A1MAPK1MEN1KMT2A
SCHEMBL8040040 0.79 ALDH1A1 (0.74) MAPTALDH1A1MAPK1MEN1KMT2A
SCHEMBL2839419 0.79 MAPT (1.00) MAPTALDH1A1MAPK1MEN1KMT2A
SCHEMBL71118 0.79 MAPT (0.74) MAPTALDH1A1MAPK1MEN1KMT2A
SCHEMBL29568790 0.79 MAPT (0.74) MAPTALDH1A1MAPK1MEN1KMT2A
SCHEMBL461660 0.78 ALDH1A1 (1.00) MAPTALDH1A1MAPK1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0830256-A2 TEMPORARY MARKING, ULTRAVIOLET RADIATION DETECTION, AND PRINTING, ALL USING PHOTOERASABLE COLORANTS Kimberly-Clark Worldwide, Inc. (US) 1998-03-25 EP disclosed
WO-1996039302-A2 TEMPORARY MARKING, ULTRAVIOLET RADIATION DETECTION, AND PRINTING, ALL USING PHOTOERASABLE COLORANTS KIMBERLY-CLARK WORLDWIDE, INC. (US) 1996-12-12 WO disclosed