SCHEMBL3453760

SCHEMBL3453760

O=C(O)c1ccc2c(c1Cl)C(=O)c1ccccc1C2=O

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 10/20 0.66
ALDH1A1 P00352 6/20 0.66
MAPK1 P28482 6/20 0.66
MEN1 O00255 5/20 0.66
KMT2A Q03164 5/20 0.66
LMNA P02545 2/20 0.66
POLB P06746 2/20 0.66
THRB P10828 2/20 0.66
RECQL P46063 2/20 0.66
L3MBTL1 Q9Y468 1/20 0.64
SMN1; SMN2 Q16637 3/20 0.60
KDM4E B2RXH2 3/20 0.60
MMP14 P50281 1/20 0.60
PKM P14618 2/20 0.56
CYP1A2 P05177 1/20 0.55
CYP2D6 P10635 1/20 0.55
CYP2C9 P11712 1/20 0.55
TSHR P16473 1/20 0.55
CYP2C19 P33261 1/20 0.55
SOS1 Q07889 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27642810 0.93 MAPT (0.64) MAPTALDH1A1MAPK1MEN1KMT2A
SCHEMBL11411791 0.81 FTO (0.73) MAPTALDH1A1MAPK1MEN1KMT2A
SCHEMBL68628 0.81 MAPT (0.68) MAPTALDH1A1MAPK1MEN1KMT2A
SCHEMBL10688917 0.80 ALDH1A1 (0.50) MAPTALDH1A1MAPK1MEN1KMT2A
SCHEMBL8635199 0.79 MAPT (0.66) MAPTALDH1A1MAPK1MEN1KMT2A
SCHEMBL8040040 0.79 ALDH1A1 (0.74) MAPTALDH1A1MAPK1MEN1KMT2A
SCHEMBL2839419 0.79 MAPT (1.00) MAPTALDH1A1MAPK1MEN1KMT2A
SCHEMBL71118 0.79 MAPT (0.74) MAPTALDH1A1MAPK1MEN1KMT2A
SCHEMBL29568790 0.79 MAPT (0.74) MAPTALDH1A1MAPK1MEN1KMT2A
SCHEMBL9717004 0.79 TTR (0.55) MAPTALDH1A1MAPK1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4308558-A None JP disclosed
JP-5117215-A None JP disclosed
EP-2196505-B1 PIGMENT COMPOSITION FOR COLOR FILTER AND COLORING COMPOSITION FOR COLOR FILTER TOYO INK MFG CO (JP) 2014-03-05 EP disclosed
EP-2196505-A1 PIGMENT COMPOSITION FOR COLOR FILTER AND COLORING COMPOSITION FOR COLOR FILTER Toyo Ink Mfg. Co. Ltd. (JP) 2010-06-16 EP disclosed
EP-0820483-B1 METHOD OF PHOTOCHEMICAL IMMOBILIZATION OF LIGANDS USING QUINONES JAKOBSEN MOGENS HAVSTEEN (DK) 2000-12-13 EP disclosed
US-6033784-A Method of photochemical immobilization of ligands using quinones JAKOBSEN MOGENS HAVSTEEN (DK) 2000-03-07 US disclosed
US-5747206-A Electrophotographic photoreceptor FUJI XEROX CO., LTD. (JP) 1998-05-05 US disclosed
EP-0820483-A1 METHOD OF PHOTOCHEMICAL IMMOBILIZATION OF LIGANDS USING QUINONES Jakobsen, Mogens Havsteen (DK) 1998-01-28 EP disclosed
WO-1996031557-A1 METHOD OF PHOTOCHEMICAL IMMOBILIZATION OF LIGANDS USING QUINONES JACOBSEN MOGENS HAVSTEEN (DK) 1996-10-10 WO disclosed
EP-0673348-A1 PRODUCTION OF HYDROGEN PEROXIDE GUILLET, James Edwin (CA) 1995-09-27 EP disclosed
US-5132437-A From 2-Substituted Benzyl Compound and Xylene HOECHST CELANESE CORPORATION (US) 1992-07-21 US disclosed
US-5130448-A Condensing ortho substituted benzoic acid and xylene, oxidation, ring closure, ammonolysis and decarboxyalation HOECHST CELANESE CORPORATION (US) 1992-07-14 US disclosed
US-4797347-A Process for producing electrically conductive coating CIBA-GEIGY CORPORATION (US) 1989-01-10 US disclosed
US-4677155-A Anthroquinonyl photosensitive polymers CIBA-GEIGY CORPORATION (US) 1987-06-30 US disclosed
EP-0112718-B1 NOVEL POLYESTER, ADHESIVES COMPRISING IT, AND LAMINATES MADE OF IT KURARAY CO., LTD. (JP) 1987-03-18 EP disclosed
US-4504531-A Polyester, adhesives comprising the same, and laminates and laminated hollow vessels made thereof KURARAY CO., LTD. (JP) 1985-03-12 US disclosed
US-4496714-A CONTAINING ORGANOALUMINUM COMPOUND KURARAY CO., LTD. (JP) 1985-01-29 US disclosed
EP-0112718-A1 Novel polyester, adhesives comprising it, and laminates made of it KURARAY CO., LTD. (JP) 1984-07-04 EP disclosed
US-4329456-A ACYLATION WITHOUT INTERMEDIATE ISOLATION CIBA-GEIGY AG (CH) 1982-05-11 US disclosed
US-4265633-A Process for the manufacture of vat dyes CIBA-GEIGY AG (CH) 1981-05-05 US disclosed