SCHEMBL8635319

SCHEMBL8635319

Oc1ccc(Oc2ncc(C(F)(F)F)cc2Cl)c(Cl)c1

nearest known ligand 0.66

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 1/20 0.66
CYP1A2 P05177 1/20 0.60
CYP3A4 P08684 1/20 0.60
CYP2C19 P33261 1/20 0.60
HPGD P15428 3/20 0.57
SMN1; SMN2 Q16637 4/20 0.51
KMT2A Q03164 1/20 0.51
LMNA P02545 4/20 0.51
ALDH1A1 P00352 2/20 0.47
LIPE Q05469 1/20 0.47
KDM4E B2RXH2 1/20 0.47
POLB P06746 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
HTT P42858 1/20 0.46
MRGPRX4 Q96LA9 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8632064 0.89 RAB9A (0.53) RAB9ACYP1A2CYP3A4CYP2C19HPGD
SCHEMBL3748894 0.83 CYP1A2 (0.60) RAB9ACYP1A2CYP3A4CYP2C19HPGD
SCHEMBL5687596 0.83 RAB9A (0.73) RAB9ACYP1A2CYP3A4CYP2C19HPGD
SCHEMBL31251923 0.83 RAB9A (0.73) RAB9ACYP1A2CYP3A4CYP2C19HPGD
SCHEMBL3220986 0.82 RAB9A (0.58) RAB9ACYP1A2CYP3A4CYP2C19HPGD
SCHEMBL3213488 0.82 RAB9A (0.58) RAB9ACYP1A2CYP3A4CYP2C19HPGD
SCHEMBL8409220 0.82 RAB9A (0.52) RAB9ACYP1A2CYP3A4CYP2C19HPGD
SCHEMBL8638013 0.82 CYP1A2 (0.58) RAB9ACYP1A2CYP3A4CYP2C19HPGD
SCHEMBL5592490 0.82 CYP1A2 (0.55) RAB9ACYP1A2CYP3A4CYP2C19HPGD
SCHEMBL8632798 0.81 RAB9A (0.63) RAB9ACYP1A2CYP3A4CYP2C19HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648729-B1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL CO (JP) 1998-07-15 EP disclosed
US-5698702-A INTERMEDIATES FOR INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-12-16 US disclosed
US-5530015-A Dihaloprene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient, and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-06-25 US disclosed
EP-0648729-A1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-04-19 EP disclosed