SCHEMBL8635378

SCHEMBL8635378

C=CCc1cc(Oc2ccc(OCC)cc2)ccc1O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 2/20 0.51
GABRA1 P14867 5/20 0.51
GABRB2 P47870 5/20 0.51
PTPN1 P18031 3/20 0.49
POLB P06746 3/20 0.44
KDM4E B2RXH2 1/20 0.42
MAPT P10636 3/20 0.41
GAA P10253 2/20 0.41
CNR1 P21554 2/20 0.41
CNR2 P34972 2/20 0.41
MEN1 O00255 1/20 0.41
ALOX5 P09917 1/20 0.41
GABRB1 P18505 1/20 0.41
RXRA P19793 1/20 0.41
GABRA5 P31644 1/20 0.41
GABRA3 P34903 1/20 0.41
GABRA2 P47869 1/20 0.41
KMT2A Q03164 1/20 0.41
ACE2 Q9BYF1 1/20 0.41
SIRT3 Q9NTG7 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9614914 0.91 GABRA1 (0.56) GABRA1GABRB2PTPN1POLBKDM4E
SCHEMBL1951863 0.87 GABRA1 (0.63) GABRA1GABRB2PTPN1POLBKDM4E
SCHEMBL5208440 0.85 GABRA1 (0.53) GABRA1GABRB2PTPN1POLBKDM4E
SCHEMBL774628 0.83 GABRA1 (0.54) LTA4HGABRA1GABRB2POLBKDM4E
SCHEMBL8636430 0.83 LTA4H (0.59) LTA4HPTPN1POLBKDM4EMAPT
SCHEMBL3550152 0.82 GABRA1 (0.53) GABRA1GABRB2POLBKDM4EMAPT
SCHEMBL5972997 0.82 GABRA1 (0.53) GABRA1GABRB2PTPN1POLBKDM4E
SCHEMBL8633405 0.81 GABRA1 (0.49) GABRA1GABRB2PTPN1POLBKDM4E
SCHEMBL8637743 0.80 LTA4H (0.56) LTA4HPTPN1POLBKDM4EMAPT
SCHEMBL5209444 0.79 POLB (0.58) GABRA1GABRB2PTPN1POLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648729-B1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL CO (JP) 1998-07-15 EP disclosed
US-5698702-A INTERMEDIATES FOR INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-12-16 US disclosed
US-5530015-A Dihaloprene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient, and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-06-25 US disclosed
EP-0648729-A1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-04-19 EP disclosed