Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 5/20 | 0.54 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 3/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1951863 | 0.92 | GABRA1 (0.63) | GABRA1GABRB2POLBAKR1B1MEN1 | |
| SCHEMBL5208440 | 0.86 | GABRA1 (0.53) | GABRA1GABRB2POLBAKR1B1MEN1 | |
| SCHEMBL5972997 | 0.86 | GABRA1 (0.53) | GABRA1GABRB2POLBAKR1B1MEN1 | |
| SCHEMBL3550152 | 0.86 | GABRA1 (0.53) | GABRA1GABRB2POLBAKR1B1MEN1 | |
| SCHEMBL9445337 | 0.86 | AKR1C3 (0.56) | GABRA1GABRB2POLBAKR1B1KMT2A | |
| Diphenylether SCHEMBL27761425 | 0.85 | GABRA1 (0.46) | GABRA1GABRB2POLBAKR1B1GAA | |
| SCHEMBL1821608 | 0.84 | LTA4H (0.44) | MEN1KMT2AGAALTA4HNR1H2 | |
| SCHEMBL8635378 | 0.83 | LTA4H (0.51) | GABRA1GABRB2POLBAKR1B1MEN1 | |
| SCHEMBL9092426 | 0.83 | GABRA1 (0.50) | GABRA1GABRB2POLBAKR1B1MEN1 | |
| SCHEMBL29106728 | 0.82 | MEN1 (0.41) | MEN1KMT2AGAAMAPTLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9700851-B2 | Phenol crosslink for sensor membrane | WAVEFORM TECHNOLOGIES, INC. (US) | 2017-07-11 | — | — | US | disclosed |
| US-9700851-B2 | Phenol crosslink for sensor membrane | WAVEFORM TECHNOLOGIES, INC. (US) | 2017-07-11 | — | — | US | disclosed |
| US-9505700-B2 | High refractive index (meth) acrylates | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-11-29 | — | — | US | disclosed |
| EP-2864285-B1 | HIGH REFRACTIVE INDEX (METH)ACRYLATES | COUNCIL SCIENT IND RES (IN) | 2016-10-19 | — | — | EP | disclosed |
| US-20150321991-A1 | HIGH REFRACTIVE INDEX (METH) ACRYLATES | COUNCIL SCIENT IND RES (IN) | 2015-11-12 | — | — | US | disclosed |
| EP-2864285-A1 | HIGH REFRACTIVE INDEX (METH) ACRYLATES | Council of Scientific & Industrial Research (IN) | 2015-04-29 | — | — | EP | disclosed |
| WO-2013190575-A1 | HIGH REFRACTIVE INDEX (METH) ACRYLATES | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2013-12-27 | — | — | WO | disclosed |
| US-20120067734-A1 | PHENOL CROSSLINK FOR SENSOR MEMBRANE | BAYER HEALTHCARE LLC (US) | 2012-03-22 | — | — | US | disclosed |
| US-20120067734-A1 | PHENOL CROSSLINK FOR SENSOR MEMBRANE | BAYER HEALTHCARE LLC (US) | 2012-03-22 | — | — | US | disclosed |
| US-20070276138-A1 | Modulators of peroxisome proliferator activated receptors | BROOKS DAWN A | 2007-11-29 | — | — | US | disclosed |
| US-6160000-A | Antidiabetic agents based on aryl and heteroarylacetic acids | MERCK & CO., INC. (US) | 2000-12-12 | — | — | US | disclosed |
| EP-1040102-A1 | ARYLTHIAZOLIDINEDIONE DERIVATIVES | Merck & Co., Inc. (US) | 2000-10-04 | — | — | EP | disclosed |
| US-6090839-A | REDUCING TRIGLYCERIDE CONCENTRATION | MERCK & CO., INC. (US) | 2000-07-18 | — | — | US | disclosed |
| US-6008237-A | POTENT AGONISTS OF PEROXIDSOME PROLIFERATOR ACTIVATED RECEPTOR; FOR CONTROLLING OR PREVENTING OF DIABETES, HYPERGLYCEMIA, HYPERLIPIDEMIA, HYPERCHOLESTEROLEMIA, ATHEROSCLEROSIS, OBESITY, VASCULAR RESTENOSIS | MERCK & CO., INC. (US) | 1999-12-28 | — | — | US | disclosed |
| EP-0948327-A1 | ANTIDIABETIC AGENTS | Merck & Co., Inc. (US) | 1999-10-13 | — | — | EP | disclosed |
| WO-1999032465-A1 | ARYLTHIAZOLIDINEDIONE DERIVATIVES | MERCK & CO., INC. (US) | 1999-07-01 | — | — | WO | disclosed |
| WO-1998027974-A1 | ANTIDIABETIC AGENTS | MERCK & CO., INC. (US) | 1998-07-02 | — | — | WO | disclosed |
| US-4465855-A | ANTIREUMATIC & ANTIINFLAMMATORIES | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT (HU) | 1984-08-14 | — | — | US | disclosed |
| US-4385004-A | Esters of ortho-allylphenol useful for the preparation of arylacetic acid derivatives | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1983-05-24 | — | — | US | disclosed |
| US-4317920-A | ANTIRHEUMATIC AGENTS, ANTIINFLAMMATORY AGENTS | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1982-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070276138-A1 | Modulators of peroxisome proliferator activated receptors | PPARG, NCOA4, PPARA | GABRA1 580/4885GABRB2 340/4885POLB 2592/4885 |
| US-20150321991-A1 | HIGH REFRACTIVE INDEX (METH) ACRYLATES | MKI67, ACR, VIM | GABRA1 1102/4885GABRB2 2628/4885POLB 3916/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.