Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NQO1 | P15559 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3187007 | 0.84 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2MAPTLMNAHPGD | |
| SCHEMBL27833941 | 0.82 | CYP3A4 (0.41) | ALDH1A1MEN1KMT2AKDM4EL3MBTL1 | |
| SCHEMBL14009819 | 0.79 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2MAPTLMNAHPGD | |
| SCHEMBL8636320 | 0.78 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2MAPTLMNAHPGD | |
| SCHEMBL8632279 | 0.77 | FBP1 (0.46) | ALDH1A1SMN1; SMN2MAPTLMNAHPGD | |
| SCHEMBL8632285 | 0.77 | FBP1 (0.46) | ALDH1A1SMN1; SMN2MAPTLMNAHPGD | |
| SCHEMBL342467 | 0.75 | NQO1 (0.64) | ALDH1A1SMN1; SMN2MAPTLMNAHPGD | |
| SCHEMBL8635260 | 0.75 | POLB (0.45) | ALDH1A1SMN1; SMN2MAPTLMNAHPGD | |
| SCHEMBL8759620 | 0.74 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2MAPTLMNAHPGD | |
| SCHEMBL8634785 | 0.74 | SLC6A4 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0717746-B1 | PHOSPHINIC ACID DERIVATIVES WITH ANTI-HYPER GLYCEMIC AND/OR ANTI-OBESITY ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 1998-07-15 | — | — | EP | disclosed |
| EP-0717746-A1 | PHOSPHINIC ACID DERIVATIVES WITH ANTI-HYPER GLYCEMIC AND/OR ANTI-OBESITY ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 1996-06-26 | — | — | EP | disclosed |
| WO-1995007284-A1 | PHOSPHINIC ACID DERIVATIVES WITH ANTI-HYPER GLYCEMIC AND/OR ANTI-OBESITY ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 1995-03-16 | — | — | WO | disclosed |