Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 7/20 | 0.43 |
| ▸ | FEN1 | P39748 | 7/20 | 0.43 |
| ▸ | F10 | P00742 | 11/20 | 0.42 |
| ▸ | F2 | P00734 | 3/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8634424 | 0.88 | ALOX5AP (0.45) | ALOX5APFEN1F10F2PRSS1 | |
| SCHEMBL8632643 | 0.87 | PTGS2 (0.53) | ALOX5APFEN1F10PTGS2 | |
| SCHEMBL8628116 | 0.87 | ALOX5AP (0.41) | ALOX5APFEN1F10F2PRSS1 | |
| SCHEMBL8634888 | 0.86 | F10 (0.43) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8629226 | 0.86 | PTGS2 (0.49) | ALOX5APFEN1F10F2PRSS1 | |
| SCHEMBL7779599 | 0.86 | PTGS2 (0.48) | PTGS2 | |
| SCHEMBL8631512 | 0.85 | LMNA (0.46) | ALOX5APFEN1F10F2PRSS1 | |
| SCHEMBL8634904 | 0.84 | ALOX5AP (0.47) | ALOX5APFEN1F10F2PRSS1 | |
| SCHEMBL8635023 | 0.84 | FEN1 (0.44) | ALOX5APFEN1F10F2PRSS1 | |
| SCHEMBL8635543 | 0.84 | PTGIR (0.51) | F10F2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |