Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | F10 | P00742 | 5/20 | 0.41 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8629226 | 0.90 | PTGS2 (0.49) | PTGIRCA1CA2CA9F10 | |
| SCHEMBL8634432 | 0.90 | PTGS2 (0.44) | PTGIRF10F2PRSS1PRSS2 | |
| SCHEMBL8634888 | 0.90 | F10 (0.43) | PTGIRCA1CA2CA9F10 | |
| SCHEMBL8628679 | 0.87 | MEN1 (0.58) | F10F2MEN1KMT2ASCN9A | |
| SCHEMBL8629705 | 0.84 | PTGIR (0.43) | PTGIRCA1CA2CA9F10 | |
| SCHEMBL8635525 | 0.84 | ALOX5AP (0.43) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7773166 | 0.84 | PTGIR (0.56) | PTGIRCA1CA2CA9PTGS2 | |
| SCHEMBL8631182 | 0.83 | PTGS2 (0.44) | PTGIRCA1CA2CA9PTGS2 | |
| SCHEMBL8632643 | 0.81 | PTGS2 (0.53) | F10PTGS2MEN1KMT2A | |
| SCHEMBL8631526 | 0.81 | ROS1 (0.40) | PTGIRCA1CA2CA9F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |