Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | F10 | P00742 | 16/20 | 0.48 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8634888 | 0.88 | F10 (0.43) | MEN1KMT2AF10F2RAB9A | |
| SCHEMBL8631931 | 0.88 | MEN1 (0.49) | MEN1KMT2AF10SCN9AF2 | |
| SCHEMBL8635543 | 0.87 | PTGIR (0.51) | MEN1KMT2AF10SCN9AF2 | |
| SCHEMBL8632189 | 0.87 | MEN1 (0.50) | MEN1KMT2AF10SCN9AF2 | |
| SCHEMBL8629226 | 0.85 | PTGS2 (0.49) | MEN1KMT2AF10F2 | |
| SCHEMBL8634432 | 0.85 | PTGS2 (0.44) | MEN1KMT2AF10F2 | |
| SCHEMBL8632643 | 0.85 | PTGS2 (0.53) | MEN1KMT2AF10 | |
| SCHEMBL8627595 | 0.85 | F10 (0.48) | MEN1KMT2AF10SCN9AF2 | |
| SCHEMBL7779737 | 0.84 | MEN1 (0.67) | MEN1KMT2A | |
| SCHEMBL8629361 | 0.84 | TGFBR1 (0.53) | F10SCN9AF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |