Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.60 |
| ▸ | HTR1A | P08908 | 2/20 | 0.60 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.56 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.52 |
| ▸ | DPP4 | P27487 | 1/20 | 0.48 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.48 |
| ▸ | CPS1 | P31327 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8638699 | 0.89 | HTR1A (0.56) | SLC6A4HTR1AMTNR1BCPS1MEN1 | |
| SCHEMBL8635447 | 0.89 | MTNR1B (0.67) | SLC6A4HTR1AMTNR1BCPS1MEN1 | |
| SCHEMBL8637331 | 0.89 | MTNR1B (0.71) | SLC6A4HTR1AMTNR1BCPS1KMT2A | |
| SCHEMBL8633694 | 0.88 | SLC6A4 (0.55) | SLC6A4HTR1AMTNR1BCPS1MEN1 | |
| SCHEMBL8635354 | 0.88 | SLC6A4 (0.55) | SLC6A4HTR1AMTNR1BCPS1MEN1 | |
| SCHEMBL8636963 | 0.88 | HTR1A (0.61) | SLC6A4HTR1AMTNR1BMEN1POLB | |
| SCHEMBL8637276 | 0.87 | SLC6A4 (0.54) | SLC6A4HTR1AMTNR1BCPS1MEN1 | |
| SCHEMBL8636883 | 0.87 | MTNR1B (0.65) | SLC6A4HTR1AMTNR1BCPS1KMT2A | |
| SCHEMBL8635044 | 0.87 | MTNR1B (0.65) | SLC6A4HTR1AMTNR1BCPS1KMT2A | |
| SCHEMBL8635648 | 0.86 | SLC6A4 (0.53) | SLC6A4HTR1AMTNR1BCPS1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0718286-B1 | 3-Alkoxybenzylpiperidine derivatives as melatonergic agents | BRISTOL MYERS SQUIBB CO (US) | 1998-07-29 | — | — | EP | claimed |
| EP-0718286-A1 | 3-Alkoxybenzylpiperidine derivatives as melatonergic agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-06-26 | — | — | EP | claimed |
| JP-8208603-A | — | — | None | — | — | JP | disclosed |
| JP-H08208603-A | 3-ALKOXYBENZYLPIPERIDINE DERIVATIVE AS MELATONERGIC AGENT | BRISTOL MYERS SQUIBB CO | 1996-08-13 | — | — | JP | disclosed |