Orthocresol

Orthocresol

SCHEMBL8635683

Cc1cccc(C)c1O.Cc1ccccc1O

nearest known ligand 0.74

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.74
TRPA1 O75762 2/20 0.71
ATM Q13315 1/20 0.56
CYP1A2 P05177 2/20 0.52
CYP2C19 P33261 1/20 0.52
GABRA1 P14867 1/20 0.48
GABRB2 P47870 1/20 0.48
HSD17B10 Q99714 5/20 0.48
HPGD P15428 4/20 0.48
LMNA P02545 4/20 0.48
RECQL P46063 3/20 0.48
ALOX15 P16050 3/20 0.48
EGFR P00533 2/20 0.48
CA2 P00918 2/20 0.48
FYN P06241 2/20 0.48
MMP9 P14780 2/20 0.48
TDP1 Q9NUW8 2/20 0.48
ADAMTS4 O75173 1/20 0.48
CA1 P00915 1/20 0.48
MMP2 P08253 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Orthocresol SCHEMBL9805651 0.91 ALDH1A1 (0.61) ALDH1A1TRPA1ATMCYP1A2CYP2C19
Orthocresol SCHEMBL11149192 0.91 ALDH1A1 (0.61) ALDH1A1TRPA1ATMCYP1A2CYP2C19
Pyrogallol SCHEMBL8609213 0.90 TRPA1 (0.71) ALDH1A1TRPA1ATMCYP1A2CYP2C19
Orthocresol SCHEMBL170162 0.89 TRPA1 (0.60) ALDH1A1TRPA1ATMCYP1A2CYP2C19
Orthocresol SCHEMBL16002 0.89
Orthocresol SCHEMBL8710164 0.89 TRPA1 (0.60) ALDH1A1TRPA1ATMCYP1A2CYP2C19
Orthocresol SCHEMBL10419161 0.89 TRPA1 (0.60) ALDH1A1TRPA1ATMCYP1A2CYP2C19
Orthocresol SCHEMBL29395276 0.89
Orthocresol SCHEMBL9719795 0.86 TRPA1 (0.57) ALDH1A1TRPA1ATMCYP1A2CYP2C19
Orthocresol SCHEMBL3407681 0.86

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5789628-A FROM PHENOL AND CARBONYL COMPOUND DEGUSSA AKTIENGESELLSCHAFT (DE) 1998-08-04 US disclosed
US-4517389-A METAL OXIDE CATALYST, FLUIDIZED BED ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1985-05-14 US disclosed
US-4468508-A Glycidyl ether of novolak type substituted phenolic resin, process for producing the same, and encapsulating compound composed mainly of the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-08-28 US disclosed
EP-0019476-A2 Catalyst and process for producing ortho-methyl substituted phenols using it MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1980-11-26 EP disclosed
US-3953529-A IRON OXIDE, SILICA, AND CHROMIUM OXIDE CATALYST MITSUBISHI GAS CHEMICAL CO. INC. (JA) 1976-04-27 US disclosed
US-3937669-A VANADIUM OXIDE ASAHI KASEI KOGYO KABUSHIKI KAISHA (JA) 1976-02-10 US disclosed