SCHEMBL8636137

SCHEMBL8636137

CCOc1cc(Oc2ccc(OC(C)C)cc2)ccc1OCC=C(Cl)Cl

nearest known ligand 0.37

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ACACB O00763 4/20 0.36
ACACA Q13085 4/20 0.36
HTT P42858 1/20 0.35
LTA4H P09960 2/20 0.34
ALDH1A1 P00352 2/20 0.34
MAPT P10636 2/20 0.33
POLB P06746 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
PTGDR Q13258 1/20 0.33
LMNA P02545 1/20 0.33
CYP3A4 P08684 1/20 0.33
TSHR P16473 1/20 0.33
STK17B O94768 2/20 0.32
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
CYP2D6 P10635 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8634461 0.88 ACACB (0.36) ACACBACACALTA4HALDH1A1MAPT
SCHEMBL8635966 0.86 THRB (0.39) ACACBACACAHTTPOLBPTGDR
SCHEMBL8635806 0.84 ACACB (0.36) ACACBACACAHTTPOLBPTGDR
SCHEMBL8636720 0.84 ACACB (0.37) ACACBACACAHTTMAPTPOLB
SCHEMBL8632253 0.83 PPARG (0.40)
SCHEMBL8638478 0.83 ACACB (0.35) ACACBACACAHTTALDH1A1POLB
SCHEMBL8635792 0.83 THRB (0.35) ACACBACACAHTTPTGDRMEN1
SCHEMBL8634403 0.81 FFAR4 (0.43) ACACBACACAHTT
SCHEMBL8632130 0.81 FFAR4 (0.40) ACACBACACAPTGDR
SCHEMBL8638349 0.80 PTGDR (0.39) ACACBACACAHTTALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648729-B1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL CO (JP) 1998-07-15 EP disclosed
US-5698702-A INTERMEDIATES FOR INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-12-16 US disclosed
US-5530015-A Dihaloprene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient, and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-06-25 US disclosed
EP-0648729-A1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-04-19 EP disclosed