Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Tetrabuthylammonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 8/20 | 0.51 |
| ▸ | GRIK2 | Q13002 | 5/20 | 0.51 |
| ▸ | SLC1A2 | P43004 | 4/20 | 0.51 |
| ▸ | SLC1A1 | P43005 | 4/20 | 0.51 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.49 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.43 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.42 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.42 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.42 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrabuthylammonium SCHEMBL8635818 | 1.00 | GRIK1 (0.51) | GRIK1GRIK2SLC1A2SLC1A1SLC1A3 | |
| Tetrabuthylammonium SCHEMBL8633451 | 0.86 | SLC22A1 (0.41) | GRIK1GRIK2SLC1A2SLC1A1SLC22A1 | |
| Tetrabuthylammonium SCHEMBL18878886 | 0.83 | GRIK1 (0.49) | GRIK1GRIK2SLC1A2SLC1A1SLC1A3 | |
| Tetrabuthylammonium SCHEMBL18878884 | 0.83 | GRIK1 (0.49) | GRIK1GRIK2SLC1A2SLC1A1SLC1A3 | |
| Tetrahexylammonium SCHEMBL28000304 | 0.82 | GRIK1 (0.51) | GRIK1GRIK2SLC1A2SLC1A1SLC1A3 | |
| Aspartic Acid SCHEMBL7782858 | 0.82 | GRIK1 (0.54) | GRIK1GRIK2SLC1A2SLC1A1SLC1A3 | |
| Aspartic Acid SCHEMBL11269603 | 0.82 | GRIK1 (0.54) | GRIK1GRIK2SLC1A2SLC1A1SLC1A3 | |
| Aspartic Acid SCHEMBL2213924 | 0.81 | GRIK1 (0.54) | GRIK1GRIK2SLC1A2SLC1A1SLC1A3 | |
| Palmitic Acid SCHEMBL22635743 | 0.81 | GPR84 (0.63) | GRIK1GRIK2GPR84 | |
| Dodecanol SCHEMBL2214038 | 0.81 | GRIK1 (0.54) | GRIK1GRIK2SLC1A2SLC1A1SLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7003180-A | — | — | None | — | — | JP | disclosed |
| EP-0621322-B1 | Reactive polymeric dyes | MINNESOTA MINING & MFG (US) | 1998-08-26 | — | — | EP | disclosed |
| US-5741620-A | FREE RADICAL POLYMERIZABLE DYES AND A 2-ALKENYLAZLACTONE COMPOUND | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-04-21 | — | — | US | disclosed |
| US-5532111-A | COMPRISING UNITS OF AZLACTONE FUNCTIONALIZED WITH NUCLEOPHILIC DYE AND OTHER GROUPS INCLUDING FREE RADICAL POLYMERIZABLE ONES; PHOTORESIST AND COLOR PROOFING | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-07-02 | — | — | US | disclosed |
| JP-H073180-A | REACTIVE POLYMERIC DYE | MINNESOTA MINING & MFG CO <3M> | 1995-01-06 | — | — | JP | disclosed |
| US-5362812-A | PHOTORESISTS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-11-08 | — | — | US | disclosed |
| EP-0621322-A1 | Reactive polymeric dyes | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-10-26 | — | — | EP | disclosed |