Known targets — ChEMBL curated mechanism
SLC6A2SLC6A3SSTR1SSTR2SSTR3SSTR5
The experimentally established mechanism targets of Tetrabuthylammonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A1 | O15245 | 3/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.38 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrabuthylammonium SCHEMBL9008771 | 0.88 | SLC22A1 (0.43) | SLC22A1CA1 | |
| Tetrabuthylammonium SCHEMBL9008776 | 0.88 | SLC22A1 (0.43) | SLC22A1CA1 | |
| Tetrabuthylammonium SCHEMBL8635818 | 0.86 | GRIK1 (0.51) | SLC22A1GPR84GRIK1GRIK2SLC1A2 | |
| Tetrabuthylammonium SCHEMBL8635816 | 0.86 | GRIK1 (0.51) | SLC22A1GPR84GRIK1GRIK2SLC1A2 | |
| Tetrabuthylammonium SCHEMBL18878885 | 0.82 | SLC22A1 (0.44) | SLC22A1CA1GRIK1GRIK2SLC1A2 | |
| Tetrylammonium SCHEMBL7592550 | 0.82 | BHMT (0.36) | GRIK1GRIK2SLC1A2SLC1A1 | |
| Tetrabuthylammonium SCHEMBL5874730 | 0.81 | GPR84 (0.46) | SLC22A1GPR84CA1CA2 | |
| Tetrabuthylammonium SCHEMBL107244 | 0.81 | CA1 (0.53) | SLC22A1GPR84CA1CA2SLC22A2 | |
| Aspartic Acid SCHEMBL23174897 | 0.81 | SLC1A2 (0.43) | GPR84CA1S1PR1S1PR2GRIK1 | |
| Aspartic Acid SCHEMBL3676198 | 0.81 | SLC1A2 (0.43) | GPR84CA1S1PR1S1PR2GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115368558-A | Rapid ring-opening polymerization method of carboxyl salt initiated cyclic anhydride monomer | 华东理工大学 | 2022-11-22 | — | — | CN | claimed |
| CN-115368558-A | Rapid ring-opening polymerization method of carboxyl salt initiated cyclic anhydride monomer | 华东理工大学 | 2022-11-22 | — | — | CN | disclosed |
| EP-0538997-B1 | Aminoketone sensitizers for aqueous soluble photopolymer compositions | MINNESOTA MINING & MFG (US) | 1998-07-01 | — | — | EP | disclosed |
| US-5534633-A | COUMARIN SENSITIZERS FOR PHOTOPOLYMERS AND IMAGES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-07-09 | — | — | US | disclosed |
| US-5480994-A | DEVELOPMENT OF PRINTING PLATES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-01-02 | — | — | US | disclosed |
| US-5455143-A | Addition polymers | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-10-03 | — | — | US | disclosed |
| US-5415976-A | Pentaerythritol tetraacrylate free radical polymerizable with coumarin sensitizer | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-05-16 | — | — | US | disclosed |
| EP-0538997-A1 | Aminoketone sensitizers for aqueous soluble photopolymer compositions | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-04-28 | — | — | EP | disclosed |