Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 10/20 | 0.57 |
| ▸ | PPARG | P37231 | 10/20 | 0.57 |
| ▸ | PPARD | Q03181 | 7/20 | 0.57 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8642303 | 0.78 | PPARG (0.52) | PPARAPPARGPPARDLTA4HTDP1 | |
| SCHEMBL8639357 | 0.77 | LTA4H (0.52) | LTA4H | |
| SCHEMBL682000 | 0.77 | PPARA (0.71) | PPARAPPARGPPARDSLC2A1LTA4H | |
| SCHEMBL27697822 | 0.76 | ALDH1A1 (0.51) | LTA4HTDP1 | |
| SCHEMBL5375698 | 0.75 | PPARG (0.66) | PPARAPPARGPPARDSLC2A1LTA4H | |
| SCHEMBL5579003 | 0.73 | PPARA (0.77) | PPARAPPARGPPARDSLC2A1LTA4H | |
| SCHEMBL5379966 | 0.73 | PPARA (0.77) | PPARAPPARGPPARDSLC2A1LTA4H | |
| SCHEMBL5380615 | 0.73 | PPARA (0.82) | PPARAPPARGPPARDTDP1 | |
| SCHEMBL5383202 | 0.72 | PPARA (1.00) | PPARAPPARGPPARD | |
| SCHEMBL5381390 | 0.72 | PPARG (0.77) | PPARAPPARGPPARDSLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5723492-A | LTA4 hydrolase inhibitor pharmaceutical compositions and methods of use | G.D. SEARLE & CO. (US) | 1998-03-03 | — | — | US | disclosed |
| US-5719306-A | ANTIINFLAMMATORY AGENTS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |