Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8637368 | 0.84 | LTA4H (0.55) | LTA4H | |
| SCHEMBL8638399 | 0.83 | LTA4H (0.55) | LTA4HL3MBTL1 | |
| SCHEMBL8644115 | 0.80 | LTA4H (0.51) | LTA4HL3MBTL1 | |
| SCHEMBL8639333 | 0.79 | LTA4H (0.64) | LTA4H | |
| SCHEMBL8635823 | 0.77 | PPARA (0.57) | LTA4H | |
| SCHEMBL13696733 | 0.76 | LTA4H (0.54) | LTA4HL3MBTL1 | |
| Bromide SCHEMBL6049771 | 0.75 | LTA4H (0.56) | LTA4HL3MBTL1 | |
| SCHEMBL4105743 | 0.75 | ITGB3 (0.57) | LTA4HL3MBTL1 | |
| Bromide SCHEMBL6049769 | 0.75 | LTA4H (0.56) | LTA4HL3MBTL1 | |
| SCHEMBL8639936 | 0.75 | LTA4H (0.62) | LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5723492-A | LTA4 hydrolase inhibitor pharmaceutical compositions and methods of use | G.D. SEARLE & CO. (US) | 1998-03-03 | — | — | US | disclosed |
| US-5719306-A | ANTIINFLAMMATORY AGENTS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |