Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 2/20 | 0.35 |
| ▸ | CTSV | O60911 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL287087 | 0.90 | ALDH1A1 (0.57) | ALDH1A1LMNAMAPK1TSHRKDM4E | |
| SCHEMBL11845297 | 0.75 | ALDH1A1 (0.41) | ALDH1A1LMNAMAPK1TSHRKDM4E | |
| SCHEMBL2996683 | 0.74 | ALDH1A1 (0.44) | ALDH1A1LMNAMAPK1TSHRKDM4E | |
| SCHEMBL11848005 | 0.74 | ALDH1A1 (0.44) | ALDH1A1LMNAMAPK1TSHRKDM4E | |
| SCHEMBL11728556 | 0.74 | ALDH1A1 (0.44) | ALDH1A1LMNAMAPK1TSHRKDM4E | |
| SCHEMBL8174209 | 0.74 | DAO (0.63) | ALDH1A1LMNAMAPK1TSHRKDM4E | |
| SCHEMBL8629968 | 0.74 | DAO (0.63) | ALDH1A1LMNAMAPK1TSHRKDM4E | |
| SCHEMBL248005 | 0.73 | SMN1; SMN2 (0.43) | ALDH1A1LMNAMAPK1TSHRKDM4E | |
| SCHEMBL17367390 | 0.71 | PLA2G10 (0.49) | ALDH1A1LMNAMAPK1TSHRKDM4E | |
| SCHEMBL10397862 | 0.71 | ALDH1A1 (0.48) | ALDH1A1LMNAMAPK1TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0852498-A1 | PHOSPHORYLAMIDES, THEIR PREPARATION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1998-07-15 | — | — | EP | disclosed |
| WO-1997011705-A1 | PHOSPHORYLAMIDES, THEIR PREPARATION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-04-03 | — | — | WO | disclosed |