Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.45 |
| ▸ | OPRL1 | P41146 | 6/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.44 |
| ▸ | CCR1 | P32246 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22122626 | 0.85 | OPRM1 (0.45) | SLC6A3OPRL1OPRM1OPRK1CCR1 | |
| SCHEMBL31279685 | 0.85 | OPRM1 (0.45) | SLC6A3OPRL1OPRM1OPRK1CCR1 | |
| SCHEMBL9827270 | 0.85 | OPRM1 (0.47) | SLC6A3SLC6A4OPRL1OPRM1OPRK1 | |
| SCHEMBL8636073 | 0.81 | SLC6A3 (0.38) | SLC6A3SLC6A4OPRL1OPRM1OPRK1 | |
| SCHEMBL8636069 | 0.81 | SLC6A3 (0.38) | SLC6A3SLC6A4OPRL1OPRM1OPRK1 | |
| SCHEMBL10699371 | 0.80 | OPRM1 (0.43) | OPRL1OPRM1OPRK1 | |
| SCHEMBL17186769 | 0.79 | SLC6A3 (0.51) | SLC6A3SLC6A4OPRL1OPRM1OPRK1 | |
| SCHEMBL10798909 | 0.78 | OPRM1 (0.39) | SLC6A3SLC6A4OPRL1OPRM1OPRK1 | |
| SCHEMBL2856214 | 0.78 | OPRL1 (0.54) | SLC6A3SLC6A4OPRL1OPRM1OPRK1 | |
| SCHEMBL16038271 | 0.77 | OPRM1 (0.43) | SLC6A3OPRL1OPRM1OPRK1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163200-B2 | Cyclohexene compounds for liquid-crystalline mixtures | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 2012-04-24 | — | — | US | disclosed |
| US-8163200-B2 | Cyclohexene compounds for liquid-crystalline mixtures | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 2012-04-24 | — | — | US | disclosed |
| EP-2052055-B1 | CYCLOHEXENE COMPOUNDS FOR LIQUID-CRYSTALLINE MIXTURES | MERCK PATENT GMBH (DE) | 2011-07-06 | — | — | EP | disclosed |
| US-20100237285-A1 | CYCLOHEXENE COMPOUNDS FOR LIQUID-CRYSTALLINE MIXTURES | MERCK PATENT GESELLSCHAFT (DE) | 2010-09-23 | — | — | US | disclosed |
| US-20100237285-A1 | CYCLOHEXENE COMPOUNDS FOR LIQUID-CRYSTALLINE MIXTURES | MERCK PATENT GESELLSCHAFT (DE) | 2010-09-23 | — | — | US | disclosed |
| WO-2008019743-A1 | CYCLOHEXENE COMPOUNDS FOR LIQUID-CRYSTALLINE MIXTURES | MERCK PATENT GMBH (DE) | 2008-02-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100237285-A1 | CYCLOHEXENE COMPOUNDS FOR LIQUID-CRYSTALLINE MIXTURES | C1S, CHRM1, C1R | SLC6A3 2849/4885SLC6A4 3174/4885OPRL1 2065/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.