Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4329451 | 0.95 | MAPT (0.35) | MAPTALDH1A1CYP1A2CYP2C9HPGD | |
| SCHEMBL726708 | 0.95 | MAPT (0.35) | MAPTALDH1A1CYP1A2CYP2C9HPGD | |
| SCHEMBL8130796 | 0.88 | CYP1A2 (0.41) | MAPTALDH1A1CYP1A2CYP2C9HPGD | |
| SCHEMBL11619938 | 0.83 | ALDH1A1 (0.39) | ALDH1A1MAPK1 | |
| Trolamine SCHEMBL28683075 | 0.80 | MAPT (0.40) | MAPTALDH1A1CYP1A2CYP2C9HPGD | |
| SCHEMBL10901378 | 0.80 | — | — | |
| Trolamine SCHEMBL8470603 | 0.79 | ALDH1A1 (0.53) | MAPTALDH1A1CYP1A2CYP2C9HPGD | |
| Trolamine SCHEMBL8012449 | 0.79 | CYP1A2 (0.35) | MAPTALDH1A1CYP1A2CYP2C9HPGD | |
| Hydroxyamine SCHEMBL6517648 | 0.79 | TDP1 (0.38) | MAPTALDH1A1CYP1A2CYP2C9HPGD | |
| SCHEMBL1720698 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512423-B1 | Aqueous solutions of cationic polyamidoamine resins | HOECHST AG (DE) | 1998-07-22 | — | — | EP | claimed |