Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.52 |
| ▸ | CA1 | P00915 | 4/20 | 0.52 |
| ▸ | CA9 | Q16790 | 4/20 | 0.52 |
| ▸ | CA4 | P22748 | 3/20 | 0.52 |
| ▸ | CA5A | P35218 | 3/20 | 0.52 |
| ▸ | CA7 | P43166 | 3/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.52 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.52 |
| ▸ | CA3 | P07451 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.35 |
| ▸ | CA6 | P23280 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
| ▸ | GRB2 | P62993 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11329370 | 0.79 | KDM4E (0.43) | CA12CA9CA4CA7CA14 | |
| SCHEMBL2808427 | 0.76 | CA12 (0.59) | CA12CA1CA9CA4CA5A | |
| SCHEMBL2221048 | 0.75 | HSD17B3 (0.47) | KDM4EALDH1A1GAAHPGDKMT2A | |
| SCHEMBL155968 | 0.75 | ALDH1A1 (0.53) | CA12CA1CA9CA4CA5A | |
| SCHEMBL20562386 | 0.75 | MAOB (0.45) | MAOBTSHRKDM4EALDH1A1HPGD | |
| SCHEMBL1461606 | 0.73 | CA9 (0.57) | CA12CA9MAOBTSHRAKR1B1 | |
| SCHEMBL6110823 | 0.72 | CA12 (0.66) | CA12CA1CA9CA4CA5A | |
| SCHEMBL1935280 | 0.71 | GPR35 (0.61) | CA12CA1CA9CA4CA5A | |
| SCHEMBL308211 | 0.71 | HSD17B3 (0.56) | MAOBKDM4EALDH1A1GAAHPGD | |
| SCHEMBL6226762 | 0.71 | MCL1 (0.51) | AKR1B1KDM4EALDH1A1LCKFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0852008-A2 | REDUCING BACKGROUND IN BIOTIN-BASED ASSAYS | Kirkegaard & Perry Laboratories, Inc. (US) | 1998-07-08 | — | — | EP | disclosed |
| WO-1997007388-A2 | REDUCING BACKGROUND IN BIOTIN-BASED ASSAYS | KIRKEGAARD & PERRY LABORATORIES, INC. (US) | 1997-02-27 | — | — | WO | disclosed |