Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | SRC | P12931 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD5 | P21918 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8636616 | 0.94 | CYP2C9 (0.50) | CYP2C9CYP2C19ALDH1A1CFTRKDM4E | |
| SCHEMBL8758097 | 0.85 | CYP2C9 (0.68) | CYP2C9CYP2C19ALDH1A1CFTRSRC | |
| SCHEMBL13858834 | 0.76 | PTPN1 (0.59) | CYP2C9CYP2C19ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL8757980 | 0.76 | CYP2C9 (0.51) | CYP2C9CYP2C19SMN1; SMN2CYP2A6MAOB | |
| SCHEMBL31173691 | 0.75 | L3MBTL1 (0.68) | ALDH1A1KDM4ESMN1; SMN2SRCCYP2A6 | |
| SCHEMBL8634990 | 0.75 | CYP2C9 (0.50) | CYP2C9CYP2C19ALDH1A1CFTRSMN1; SMN2 | |
| SCHEMBL8635599 | 0.74 | ALDH1A1 (0.46) | CYP2C9CYP2C19ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL8727310 | 0.73 | CYP2C9 (0.47) | CYP2C9CYP2C19CYP2A6MAOA | |
| SCHEMBL16350513 | 0.72 | ALDH1A1 (0.54) | ALDH1A1KDM4ESMN1; SMN2RAB9ACYP2A6 | |
| SCHEMBL8392921 | 0.72 | ALDH1A1 (0.58) | ALDH1A1KDM4ESMN1; SMN2RAB9ACYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0717746-B1 | PHOSPHINIC ACID DERIVATIVES WITH ANTI-HYPER GLYCEMIC AND/OR ANTI-OBESITY ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 1998-07-15 | — | — | EP | disclosed |
| EP-0717746-A1 | PHOSPHINIC ACID DERIVATIVES WITH ANTI-HYPER GLYCEMIC AND/OR ANTI-OBESITY ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 1996-06-26 | — | — | EP | disclosed |
| WO-1995007284-A1 | PHOSPHINIC ACID DERIVATIVES WITH ANTI-HYPER GLYCEMIC AND/OR ANTI-OBESITY ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 1995-03-16 | — | — | WO | disclosed |