⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8630321 | 0.84 | — | — | |
| SCHEMBL631735 | 0.77 | KIF11 (0.30) | — | |
| SCHEMBL1379446 | 0.73 | KIF11 (0.38) | — | |
| SCHEMBL20278 | 0.68 | CTNNB1 (0.31) | — | |
| SCHEMBL27041159 | 0.67 | — | — | |
| SCHEMBL9077845 | 0.64 | AKR1B1 (0.32) | — | |
| SCHEMBL9875356 | 0.64 | AHR (0.40) | — | |
| SCHEMBL9103991 | 0.63 | — | — | |
| SCHEMBL1656055 | 0.63 | — | — | |
| SCHEMBL10545472 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5536725-A | Insecticidal substituted-2,4-diamino-5,6,7,8-tetrahydroquinazolines | FMC CORPORATION (US) | 1996-07-16 | — | — | US | claimed |
| US-4767779-A | Pyrazoline-1-carboxamides, composition containing them, and insecticidal method of using them | FMC CORPORATION (US) | 1988-08-30 | — | — | US | claimed |
| US-5712281-A | Insecticidal substituted-2,4-diamino-5,6,7,8-tetrahydroquinazolines | FMC CORPORATION (US) | 1998-01-27 | — | — | US | disclosed |
| US-5536725-A | Insecticidal substituted-2,4-diamino-5,6,7,8-tetrahydroquinazolines | FMC CORPORATION (US) | 1996-07-16 | — | — | US | disclosed |
| EP-0357610-B1 | INSECTICIDAL CYCLOPROPYL-SUBSTITUTED DI(ARYL) COMPOUNDS | FMC Corporation (US) | 1992-09-16 | — | — | EP | disclosed |
| US-4975451-A | Insecticidal cyclopropyl di(aryl) 2-butenes | FMC CORPORATION (US) | 1990-12-04 | — | — | US | disclosed |
| EP-0357610-A1 | INSECTICIDAL CYCLOPROPYL-SUBSTITUTED DI(ARYL) COMPOUNDS. | FMC CORP (US) | 1990-03-14 | — | — | EP | disclosed |
| US-4808762-A | Insecticidal cyclopropyl-substituted di(aryl) compounds | FMC CORPORATION (US) | 1989-02-28 | — | — | US | disclosed |
| WO-1988008416-A1 | INSECTICIDAL CYCLOPROPYL-SUBSTITUTED DI(ARYL) COMPOUNDS | FMC CORPORATION (US) | 1988-11-03 | — | — | WO | disclosed |
| US-4767779-A | Pyrazoline-1-carboxamides, composition containing them, and insecticidal method of using them | FMC CORPORATION (US) | 1988-08-30 | — | — | US | disclosed |