SCHEMBL9875356

SCHEMBL9875356

FC1(F)Oc2ccc(Br)cc2C1(F)F

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
AHR P35869 3/20 0.40
BACE1 P56817 11/20 0.38
CTSD P07339 1/20 0.33
AKR1B1 P15121 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
HTT P42858 1/20 0.33
BLM P54132 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29107151 0.84 AHR (0.40) AHRBACE1LMNAMAPTHTT
SCHEMBL316417 0.77 AHR (0.50) AHRBACE1LMNAMAPTHTT
SCHEMBL31085202 0.77 AHR (0.50) AHRBACE1LMNAMAPTHTT
SCHEMBL24275672 0.76 AHR (0.40) AHRAKR1B1
SCHEMBL9874314 0.76 MAPT (0.38) MAPT
SCHEMBL20714875 0.76 MMP12 (0.36) AKR1B1MAPTHTT
SCHEMBL1722673 0.73 KIF11 (0.47) AHRBACE1CTSDLMNAMAPT
SCHEMBL3545157 0.70 AHR (0.31) AHR
SCHEMBL9349990 0.69 AHR (0.42) AHRBACE1LMNAMAPTHTT
SCHEMBL12046 0.68 AHR (0.50) AHRLMNAMAPTHTTBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5008277-A For controlling insects in agriculture FMC CORPORATION (US) 1991-04-16 US disclosed
US-4870089-A N-[(alpha-perhaloalkylbenzyloxy)pyridyl]-N'-benzoylurea insecticides FMC CORPORATION (US) 1989-09-26 US disclosed