SCHEMBL20278

SCHEMBL20278

FC1(F)Oc2c[c]ccc2O1

nearest known ligand 0.31

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CTNNB1 P35222 1/20 0.31
WNT3A P56704 1/20 0.31
GPR3 P46089 1/20 0.31
NOTUM Q6P988 1/20 0.30
PIK3CA P42336 1/20 0.30
PIK3CG P48736 1/20 0.30
KIF11 P52732 1/20 0.30
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL631735 0.86 KIF11 (0.30) KIF11
SCHEMBL2884588 0.77 TSHR (0.44) KIF11
SCHEMBL6604232 0.77
SCHEMBL1379446 0.74 KIF11 (0.38) KIF11
SCHEMBL10545472 0.72
SCHEMBL10352632 0.72
SCHEMBL16026307 0.72 GPR3 (0.31) GPR3
SCHEMBL7197139 0.71 CNR1 (0.36)
SCHEMBL12482346 0.71 BRPF1 (0.30)
SCHEMBL200514 0.69 GPR3 (0.45) CTNNB1WNT3AGPR3NOTUMPIK3CA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2347 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115872904-B N-hydroxy-N-phenyl aromatic amide derivative and application thereof 沈阳中化农药化工研发有限公司 2024-06-25 CN claimed
CN-118201911-A Compounds and their use as GPR183 inhibitors 南京艾美斐生物医药科技有限公司 2024-06-14 CN claimed
US-20230416205-A1 COMPOUNDS, COMPOSITIONS, AND METHODS TENVIE THERAPEUTICS, INC. 2023-12-28 US claimed
EP-4247376-A1 COMPOUNDS, COMPOSITIONS, AND METHODS Denali Therapeutics Inc. (US) 2023-09-27 EP claimed
WO-2023084473-A1 BICYCLIC HETEROAROMATIC COMPOUNDS AND THEIR USE AS PEST CONTROL AGENTS PI INDUSTRIES LTD. (IN) 2023-05-19 WO claimed
CN-115872904-A N-hydroxy-N-phenyl aromatic amide derivative and application thereof 沈阳中化农药化工研发有限公司 2023-03-31 CN claimed
WO-2022109268-A1 COMPOUNDS, COMPOSITIONS, AND METHODS DENALI THERAPEUTICS INC. (US) 2022-05-27 WO claimed
CN-110092788-B Substituted [1,2,4] triazolo [1,5-a ] pyrimidin-7-yl compounds as PDE2 inhibitors 达特神经科学(开曼)有限公司 2022-02-25 CN claimed
EP-3597649-B1 COMPOSITIONS CONTAINING SUBSTITUTED [1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-YL COMPOUNDS AS PDE2 INHIBITORS DART NEUROSCIENCE CAYMAN LTD (KY) 2021-10-13 EP claimed
WO-2021183702-A1 GPX4 INHIBITORS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR USE FOR TREATING GPX4-MEDIATED DISEASES EUBULUS BIOTHERAPEUTICS INC. (CN) 2021-09-16 WO claimed
US-5536725-A Insecticidal substituted-2,4-diamino-5,6,7,8-tetrahydroquinazolines FMC CORPORATION (US) 1996-07-16 US claimed
WO-1996006072-A1 OXIME ETHERS AND THEIR USE AS PESTICIDES CIBA-GEIGY AG (CH) 1996-02-29 WO claimed
EP-0651737-A1 O-BENZYL OXIME ETHER DERIVATIVES AND THEIR USE AS PESTICIDES Novartis AG (CH) 1995-05-10 EP claimed
WO-1994026700-A1 O-BENZYL OXIME ETHER DERIVATIVES AND THEIR USE AS PESTICIDES CIBA-GEIGY AG (CH) 1994-11-24 WO claimed
US-5162367-A Arylalkadienamide THE WELLCOME FOUNDATION LIMITED (GB) 1992-11-10 US claimed
US-5045566-A Phenyl or naphthyl substituted ICI AMERICAS INC. (US) 1991-09-03 US claimed
US-4883789-A Substituted phenyltrialkylsilane insecticides FMC CORPORATION (US) 1989-11-28 US claimed
US-4767779-A Pyrazoline-1-carboxamides, composition containing them, and insecticidal method of using them FMC CORPORATION (US) 1988-08-30 US claimed
EP-0212822-A1 A composition containing a plant growth regulator and an alkanol and a method of using the same ICI AMERICAS INC. (US) 1987-03-04 EP claimed
US-4043791-A Method of regulating the growth of aquatic weeds with pyridine derivatives ELI LILLY AND COMPANY (US) 1977-08-23 US claimed