Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28600471 | 0.85 | ALDH1A1 (0.53) | KDM4EALDH1A1KMT2ACES2CES1 | |
| SCHEMBL8636888 | 0.81 | NPSR1 (0.53) | KDM4EALDH1A1KMT2AATMLMNA | |
| SCHEMBL28600465 | 0.81 | KMT2A (0.50) | KDM4EALDH1A1KMT2AATMLMNA | |
| SCHEMBL28618236 | 0.81 | GAA (0.44) | ALDH1A1CES2CES1MAPTTSHR | |
| SCHEMBL28050368 | 0.80 | NPC1 (0.45) | KDM4EALDH1A1KMT2ALMNAMAPT | |
| SCHEMBL9518578 | 0.76 | NPSR1 (0.47) | ALDH1A1KMT2AATMLMNATSHR | |
| SCHEMBL27514150 | 0.75 | GAA (0.53) | KDM4EALDH1A1KMT2ALMNAMAPT | |
| SCHEMBL6256662 | 0.75 | CES2 (0.41) | KDM4EALDH1A1KMT2AATMCES2 | |
| SCHEMBL9448424 | 0.74 | ALDH1A1 (0.45) | KDM4EALDH1A1KMT2ALMNAMAPT | |
| Acetic Acid SCHEMBL29291113 | 0.73 | ALDH1A1 (0.59) | KDM4EALDH1A1KMT2AATMCES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0855387-A1 | 2-ACYLAMINOBENZAMIDE DERIVATIVES AND PREVENTIVE AND REMEDY FOR DISEASES CAUSED BY THE SUPERMULTIPLICATION OF VASCULAR INTIMAL CELLS | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1998-07-29 | — | — | EP | disclosed |