SCHEMBL8636780

SCHEMBL8636780

O=S(=O)(O)CCCOc1[c]cccc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 1/20 0.35
PLA2G2A P14555 2/20 0.34
ALDH1A1 P00352 2/20 0.33
LMNA P02545 2/20 0.33
POLB P06746 2/20 0.33
RAB9A P51151 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
NPC1 O15118 1/20 0.33
MAPT P10636 1/20 0.33
ALOX15 P16050 1/20 0.33
BRCA1 P38398 1/20 0.33
HTT P42858 1/20 0.33
KDM4E B2RXH2 1/20 0.33
GMNN O75496 1/20 0.33
PKM P14618 1/20 0.33
THPO P40225 1/20 0.33
MTOR P42345 1/20 0.33
RECQL P46063 1/20 0.33
BLM P54132 1/20 0.33
HIF1A Q16665 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8985004 0.95 ALDH1A1 (0.35) LTA4HPLA2G2AALDH1A1LMNAPOLB
SCHEMBL27997690 0.83 FFAR1 (0.33)
SCHEMBL3913149 0.81 TSHR (0.30) SMN1; SMN2
SCHEMBL6238419 0.78 JAK2 (0.33) ALDH1A1LMNASMN1; SMN2MAPTHTT
SCHEMBL8927823 0.77 APP (0.34) LTA4HPLA2G2AALDH1A1LMNAPOLB
SCHEMBL2762966 0.77 ALDH1A1 (0.38) LTA4HALDH1A1KDM4ERECQLPDE5A
SCHEMBL8622906 0.75 HTT (0.33) HTT
SCHEMBL16390799 0.75 PPARA (0.44) ALDH1A1LMNASMN1; SMN2MAPT
SCHEMBL6721192 0.74
SCHEMBL348920 0.74 ALDH1A1 (0.48) ALDH1A1SMN1; SMN2HTTRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0593177-B1 Silver halide photographic emulsion and light-sensitive silver halide photographic material KONISHIROKU PHOTO IND (JP) 1998-07-15 EP disclosed
EP-0447137-B1 Light-sensitive silver halide photographic material KONISHIROKU PHOTO IND (JP) 1995-09-13 EP disclosed
US-5403705-A Optically sensitized by addition of dispersion of particles of optical sensitizer; storage stability KONICA CORPORATION (JP) 1995-04-04 US disclosed
EP-0593177-A1 Silver halide photographic emulsion and light-sensitive silver halide photographic material KONICA CORPORATION (JP) 1994-04-20 EP disclosed
US-5204232-A Optical stability; antisoilants; aging resistance; color photography KONICA CORPORATION (JP) 1993-04-20 US disclosed
US-5120635-A Fixing or bleach-fixing solution containing a thiosulfate, a bisulfite or sulfite and a sulfo-substituted benzaldehyde or bisulfite addition product thereof; stability, reduced stain FUJI PHOTO FILM CO., LTD. (JP) 1992-06-09 US disclosed
EP-0447137-A1 Light-sensitive silver halide photographic material KONICA CORPORATION (JP) 1991-09-18 EP disclosed
EP-0432499-A1 Method for processing silver halide photographic material and composition having fixing ability FUJI PHOTO FILM CO., LTD. (JP) 1991-06-19 EP disclosed
US-4183752-A DEVELOPMENT INHIBITOR RELEASING THIOETHERS AGFA-GEVAERT AKTIENGESELLSCHAFT (DE) 1980-01-15 US disclosed