Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.30 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | DHPS | P49366 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2762966 | 0.90 | ALDH1A1 (0.38) | ALDH1A1RECQLIDO1GAAMEN1 | |
| SCHEMBL11352154 | 0.89 | KMT2A (0.40) | ALDH1A1RECQLMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6238419 | 0.87 | JAK2 (0.33) | ALDH1A1RECQLGAASMN1; SMN2HTT | |
| SCHEMBL27858367 | 0.86 | CNR2 (0.35) | ALDH1A1RECQLPDK2 | |
| SCHEMBL2008537 | 0.83 | KCNH2 (0.32) | ALDH1A1RECQL | |
| SCHEMBL584941 | 0.83 | — | — | |
| SCHEMBL8598226 | 0.82 | TDP1 (0.33) | ALDH1A1RECQL | |
| SCHEMBL188983 | 0.79 | KDM4E (0.48) | ALDH1A1MEN1KMT2ASMN1; SMN2CYP19A1 | |
| SCHEMBL126227 | 0.79 | ALDH1A1 (0.34) | ALDH1A1GAAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2458787 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 230 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3154969-B1 | PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | GILEAD SCIENCES INC (US) | 2019-10-09 | — | — | EP | claimed |
| US-10221197-B2 | Phosphatidylinositol 3-kinase inhibitors | GILEAD SCIENCES, INC. (US) | 2019-03-05 | — | — | US | claimed |
| EP-3154969-A1 | PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | GILEAD SCIENCES, INC. (US) | 2017-04-19 | — | — | EP | claimed |
| WO-2015191745-A1 | PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | GILEAD SCIENCES, INC. (US) | 2015-12-17 | — | — | WO | claimed |
| US-8218931-B2 | D 1413 HT radiation curable coatings for optical fiber | DSM IP ASSETS B.V. (NL) | 2012-07-10 | — | — | US | claimed |
| US-20100261765-A1 | MINERALOCORTICOID RECEPTOR MODULATORS | MERCK SHARP & DOHME CORP. | 2010-10-14 | — | — | US | claimed |
| EP-2229167-A1 | MINERALOCORTICOID RECEPTOR MODULATORS | Merck Sharp & Dohme Corp. (US) | 2010-09-22 | — | — | EP | claimed |
| WO-2009078934-A1 | MINERALOCORTICOID RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2009-06-25 | — | — | WO | claimed |
| US-20060035922-A1 | Triazolopyridinylsulfanyl derivatives as p38 MAP kinase inhibitors | PFIZER INC. | 2006-02-16 | — | — | US | claimed |
| EP-1036062-B1 | HYDROXAMIC ACID DERIVATIVES AS MATRIX METALLOPROTEASE (MMP) INHIBITORS | PFIZER LTD (GB) | 2004-01-02 | — | — | EP | claimed |
| EP-0495250-B1 | Cationic 1,3,4 thiadiazole dyes | BAYER AG (DE) | 1996-01-31 | — | — | EP | claimed |
| US-5288593-A | Photographic material and process comprising a coupler capable of forming a wash-out dye (Q/Q) | EASTMAN KODAK COMPANY (US) | 1994-02-22 | — | — | US | claimed |
| US-5279929-A | Coupler forms a compound that washes out during development | EASTMAN KODAK COMPANY (US) | 1994-01-18 | — | — | US | claimed |
| EP-0577182-A1 | Photographic material and process comprising a coupler capable of forming a wash-out dye (Q/Q) | EASTMAN KODAK COMPANY (US) | 1994-01-05 | — | — | EP | claimed |
| EP-0576087-A1 | Photographic material and process comprising a coupler capable of forming a wash-out dye (Q/C) | EASTMAN KODAK COMPANY (US) | 1993-12-29 | — | — | EP | claimed |
| EP-0576089-A2 | Photographic material and process comprising a coupler capable of forming a wash-out dye | EASTMAN KODAK COMPANY (US) | 1993-12-29 | — | — | EP | claimed |
| EP-0576088-A1 | Photographic material and process comprising a coupler capable of forming a wash-out dye (C/C) | EASTMAN KODAK COMPANY (US) | 1993-12-29 | — | — | EP | claimed |
| US-5270308-A | Hypotensives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-12-14 | — | — | US | claimed |
| US-5208325-A | CATIONIC 1,3,4-THIADIAZOLE DYESTUFFS | BAYER AKTIENGESELLSCHAFT (DE) | 1993-05-04 | — | — | US | claimed |
| EP-0495250-A1 | Cationic 1,3,4 thiadiazole dyes | BAYER AG (DE) | 1992-07-22 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060035922-A1 | Triazolopyridinylsulfanyl derivatives as p38 MAP kinase inhibitors | MAPK1, MAPKAPK5, MAPKAPK3 | ALDH1A1 2400/4885RECQL 4179/4885IDO1 1826/4885 |
| US-20100261765-A1 | MINERALOCORTICOID RECEPTOR MODULATORS | NR3C2, MC2R, NR3C1 | ALDH1A1 2350/4885RECQL 4642/4885IDO1 4350/4885 |
| US-10221197-B2 | Phosphatidylinositol 3-kinase inhibitors | PIK3CA, AKT3, PIK3CD | ALDH1A1 4535/4885RECQL 631/4885IDO1 3569/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.