SCHEMBL8637037

SCHEMBL8637037

Cc1cc(Oc2ncc(C(F)(F)F)cc2C(F)(F)F)ccc1OCC=C(Br)Br

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 12/20 0.39
LMNA P02545 1/20 0.37
RAB9A P51151 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
PPARA Q07869 3/20 0.36
LIPE Q05469 1/20 0.35
DRD1 P21728 1/20 0.35
PPARG P37231 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8632953 0.93 PPARD (0.40) PPARDLMNASMN1; SMN2PPARAPPARG
SCHEMBL8634647 0.90 PPARD (0.41) PPARDLMNARAB9ASMN1; SMN2PPARA
SCHEMBL8632741 0.88 RAB9A (0.44) LMNARAB9ASMN1; SMN2LIPE
SCHEMBL8638565 0.83 LMNA (0.41) LMNARAB9ASMN1; SMN2LIPE
SCHEMBL8899964 0.82 PPARD (0.41) PPARDLMNARAB9ASMN1; SMN2PPARA
SCHEMBL8635686 0.81 LMNA (0.48) LMNARAB9ASMN1; SMN2LIPE
SCHEMBL8634551 0.81 RAB9A (0.52) LMNARAB9ASMN1; SMN2LIPE
SCHEMBL8632225 0.81 CYP1A2 (0.40) LMNARAB9ASMN1; SMN2LIPE
SCHEMBL8633939 0.78 RAB9A (0.53) LMNARAB9ASMN1; SMN2LIPE
SCHEMBL8635057 0.78 RAB9A (0.45) LMNARAB9ASMN1; SMN2LIPE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648729-B1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL CO (JP) 1998-07-15 EP disclosed
US-5698702-A INTERMEDIATES FOR INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-12-16 US disclosed
US-5530015-A Dihaloprene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient, and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-06-25 US disclosed
EP-0648729-A1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-04-19 EP disclosed