Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.35 |
| ▸ | MMP9 | P14780 | 2/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 2/20 | 0.31 |
| ▸ | PPARG | P37231 | 2/20 | 0.30 |
| ▸ | PPARA | Q07869 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Famoxadone SCHEMBL673443 | 0.71 | MMP2 (0.42) | MMP2MMP9MMP3MMP8MMP13 | |
| Rubidium SCHEMBL6925069 | 0.69 | LIPG (0.53) | PPARGPPARA | |
| SCHEMBL6864718 | 0.69 | PPARA (0.43) | LTA4HPPARGPPARA | |
| SCHEMBL14947341 | 0.69 | LTA4H (0.46) | MMP2MMP9MMP3MMP8MMP13 | |
| SCHEMBL10598568 | 0.68 | LIPG (0.51) | PPARGPPARA | |
| SCHEMBL6535928 | 0.68 | LIPG (0.54) | PPARGPPARA | |
| SCHEMBL21121138 | 0.68 | LIPG (0.54) | PPARGPPARA | |
| Nonane SCHEMBL5533194 | 0.68 | LIPG (0.54) | PPARGPPARA | |
| SCHEMBL24722 | 0.68 | LIPG (0.54) | PPARGPPARA | |
| SCHEMBL153186 | 0.68 | LIPG (0.54) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0577712-B1 | FUNGICIDAL 4-THIOXOOXAZOLIDIN-2-ONES AND 4-IMINOOXAZOLINDIN-2-ONES | DU PONT (US) | 1998-07-29 | — | — | EP | disclosed |
| EP-0577712-A1 | FUNGICIDAL 4-THIOXOOXAZOLIDIN-2-ONES AND 4-IMINOOXAZOLINDIN-2-ONES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-01-12 | — | — | EP | disclosed |
| WO-1992016515-A1 | FUNGICIDAL 4-THIOXOOXAZOLIDIN-2-ONES AND 4-IMINOOXAZOLINDIN-2-ONES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-10-01 | — | — | WO | disclosed |
| EP-0503798-A1 | Fungicidal 4-thixooxazolidin-2-ones and 4-iminooxazolindin-2-ones | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-09-16 | — | — | EP | disclosed |