Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY2R | P49146 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8633965 | 0.81 | NPY2R (0.55) | NPY2RGAAKDM4EMAPTTP53 | |
| Hydrochloric Acid SCHEMBL8838195 | 0.80 | NPY2R (0.54) | NPY2RGAAKDM4EMAPTTP53 | |
| SCHEMBL15417704 | 0.76 | LMNA (0.50) | NPY2RGAAKDM4EMAPTTSHR | |
| SCHEMBL8837946 | 0.74 | NPY2R (0.53) | NPY2RGAAKDM4EMAPTTP53 | |
| SCHEMBL12361740 | 0.73 | ATM (0.49) | NPY2RGAAKDM4EMAPTTSHR | |
| SCHEMBL19697691 | 0.72 | LMNA (0.67) | NPY2RGAAMAPTCYP2C9TSHR | |
| SCHEMBL8838002 | 0.70 | HRH3 (0.53) | GAAKDM4EMAPTROCK2CYP2C9 | |
| SCHEMBL14590786 | 0.70 | ALDH1A1 (0.69) | NPY2RGAAMAPTTP53TSHR | |
| SCHEMBL8838099 | 0.70 | CHKA (0.50) | GAACYP2C9TSHRITGB3ITGA2B | |
| SCHEMBL5078059 | 0.69 | NPY2R (0.76) | NPY2RMAPTTP53LMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753659-A | ANTICOAGULANTS FOR BLOOD DISORDER, CARDIOVASCULAR DISORDER, THROMBOSIS, | ZENECA LIMITED (GB) | 1998-05-19 | — | — | US | disclosed |
| US-5728701-A | INHIBIT PLATELET AGGREGATION | ZENECA LIMITED (GB) | 1998-03-17 | — | — | US | disclosed |