Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY2R | P49146 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8838195 | 0.99 | NPY2R (0.54) | NPY2RLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL8837946 | 0.83 | NPY2R (0.53) | NPY2RLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL8633635 | 0.81 | TSHR (0.44) | NPY2RALDH1A1TP53ROCK2GAA | |
| SCHEMBL8637199 | 0.81 | NPY2R (0.48) | NPY2RLMNATP53ROCK2GAA | |
| SCHEMBL14590786 | 0.78 | ALDH1A1 (0.69) | NPY2RLMNAALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8837986 | 0.76 | ITGB3 (0.47) | ALDH1A1ROCK2GAAITGB3ITGA2B | |
| SCHEMBL5078059 | 0.76 | NPY2R (0.76) | NPY2RLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL15417704 | 0.76 | LMNA (0.50) | NPY2RLMNAALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8838087 | 0.75 | ADRB2 (0.49) | NPY2RALDH1A1ROCK2GAAITGB3 | |
| SCHEMBL12103050 | 0.74 | NPY2R (0.53) | NPY2RLMNAALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753659-A | ANTICOAGULANTS FOR BLOOD DISORDER, CARDIOVASCULAR DISORDER, THROMBOSIS, | ZENECA LIMITED (GB) | 1998-05-19 | — | — | US | disclosed |
| US-5750754-A | TERTIARY BUTYL 3-METHYL-4-SUBSTITUTED BUTYRATE; CHEMICAL INTERMEDIATES FOR ANTICAOGULANT DRUGS | ZENECA LIMITED (GB) | 1998-05-12 | — | — | US | disclosed |
| US-5728701-A | INHIBIT PLATELET AGGREGATION | ZENECA LIMITED (GB) | 1998-03-17 | — | — | US | disclosed |