Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 4/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.46 |
| ▸ | ACACB | O00763 | 5/20 | 0.43 |
| ▸ | CCNC | P24863 | 1/20 | 0.43 |
| ▸ | CDK8 | P49336 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8637204 | 0.85 | HRH3 (0.44) | F10HRH3ITGB3ITGA2BCCNC | |
| SCHEMBL7405501 | 0.84 | F10 (0.49) | F10HRH3ITGB3ITGA2BACACB | |
| SCHEMBL7398480 | 0.82 | ITGB3 (0.53) | F10HRH3ITGB3ITGA2B | |
| SCHEMBL9760074 | 0.81 | DRD2 (0.55) | F10ACACB | |
| SCHEMBL7401249 | 0.80 | F10 (0.49) | F10ACACB | |
| SCHEMBL5632401 | 0.79 | F10 (0.55) | F10HRH3 | |
| SCHEMBL9760771 | 0.79 | F10 (0.49) | F10ITGB3ITGA2BACACB | |
| SCHEMBL7398432 | 0.78 | F10 (0.48) | F10ITGB3ITGA2B | |
| SCHEMBL7336334 | 0.78 | F10 (0.46) | F10ITGB3ITGA2BACACB | |
| SCHEMBL8681292 | 0.77 | F10 (0.51) | F10HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753659-A | ANTICOAGULANTS FOR BLOOD DISORDER, CARDIOVASCULAR DISORDER, THROMBOSIS, | ZENECA LIMITED (GB) | 1998-05-19 | — | — | US | disclosed |
| US-5728701-A | INHIBIT PLATELET AGGREGATION | ZENECA LIMITED (GB) | 1998-03-17 | — | — | US | disclosed |