Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.44 |
| ▸ | F10 | P00742 | 11/20 | 0.43 |
| ▸ | CCNC | P24863 | 1/20 | 0.43 |
| ▸ | CDK8 | P49336 | 1/20 | 0.43 |
| ▸ | IKBKB | O14920 | 1/20 | 0.42 |
| ▸ | CHUK | O15111 | 1/20 | 0.42 |
| ▸ | LSS | P48449 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8637462 | 0.88 | HRH3 (0.42) | HRH3F10CCNCCDK8 | |
| SCHEMBL8637208 | 0.85 | F10 (0.49) | HRH3F10CCNCCDK8ITGB3 | |
| SCHEMBL9760077 | 0.79 | F10 (0.49) | F10SMN1; SMN2F2 | |
| SCHEMBL5634334 | 0.77 | F10 (0.47) | F10IKBKBCHUK | |
| SCHEMBL9032652 | 0.76 | KDM4E (0.51) | — | |
| SCHEMBL8637213 | 0.76 | F10 (0.44) | HRH3F10CCNCCDK8SMN1; SMN2 | |
| SCHEMBL8632715 | 0.75 | HRH3 (0.43) | HRH3F10CCNCCDK8ITGB3 | |
| SCHEMBL7405501 | 0.74 | F10 (0.49) | HRH3F10SMN1; SMN2ITGB3ITGA2B | |
| SCHEMBL6794440 | 0.72 | F10 (0.47) | HRH3F10ITGB3ITGA2B | |
| SCHEMBL7398480 | 0.71 | ITGB3 (0.53) | HRH3F10ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753659-A | ANTICOAGULANTS FOR BLOOD DISORDER, CARDIOVASCULAR DISORDER, THROMBOSIS, | ZENECA LIMITED (GB) | 1998-05-19 | — | — | US | disclosed |
| US-5728701-A | INHIBIT PLATELET AGGREGATION | ZENECA LIMITED (GB) | 1998-03-17 | — | — | US | disclosed |