Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 17/20 | 0.76 |
| ▸ | PDGFRA | P16234 | 8/20 | 0.76 |
| ▸ | RET | P07949 | 6/20 | 0.76 |
| ▸ | AURKB | Q96GD4 | 6/20 | 0.76 |
| ▸ | FLT1 | P17948 | 5/20 | 0.76 |
| ▸ | FLT4 | P35916 | 5/20 | 0.76 |
| ▸ | KIT | P10721 | 5/20 | 0.76 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.76 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.76 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.76 |
| ▸ | STK10 | O94804 | 2/20 | 0.76 |
| ▸ | ABL1 | P00519 | 2/20 | 0.76 |
| ▸ | BCR | P11274 | 2/20 | 0.76 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.76 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.76 |
| ▸ | MAP4K2 | Q12851 | 2/20 | 0.76 |
| ▸ | PTK6 | Q13882 | 2/20 | 0.76 |
| ▸ | DDR2 | Q16832 | 2/20 | 0.76 |
| ▸ | RIPK3 | Q9Y572 | 2/20 | 0.76 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31055824 | 1.00 | KDR (0.76) | KDRPDGFRARETAURKBFLT1 | |
| SCHEMBL26127786 | 0.97 | KDR (0.71) | KDRPDGFRARETAURKBFLT1 | |
| SCHEMBL31231426 | 0.97 | KDR (0.71) | KDRPDGFRARETAURKBFLT1 | |
| Maleic Acid SCHEMBL26124672 | 0.95 | KDR (0.69) | KDRPDGFRARETAURKBFLT1 | |
| Maleic Acid SCHEMBL31055823 | 0.95 | KDR (0.69) | KDRPDGFRARETAURKBFLT1 | |
| Maleic Acid SCHEMBL26124671 | 0.95 | KDR (0.69) | KDRPDGFRARETAURKBFLT1 | |
| SCHEMBL864748 | 0.93 | KDR (0.73) | KDRPDGFRARETAURKBFLT1 | |
| SCHEMBL23366513 | 0.93 | KDR (0.83) | KDRPDGFRARETAURKBFLT1 | |
| SCHEMBL1888432 | 0.92 | KDR (0.64) | KDRPDGFRARETAURKBFLT1 | |
| SCHEMBL1893312 | 0.92 | KDR (0.64) | KDRPDGFRARETAURKBFLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 156 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250177302-A1 | LIPOSOME COMPOSITION AND LIPOSOME-CONTAINING PHARMACEUTICAL COMPOSITION | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2025-06-05 | — | — | US | claimed |
| EP-4467129-A1 | LIPOSOME COMPOSITION AND LIPOSOME-CONTAINING PHARMACEUTICAL COMPOSITION | Eisai R&D Management Co., Ltd. (JP) | 2024-11-27 | — | — | EP | claimed |
| WO-2023190709-A1 | LIPOSOME COMPOSITION AND LIPOSOME-CONTAINING PHARMACEUTICAL COMPOSITION | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 2023-10-05 | — | — | WO | claimed |
| EP-2700403-B1 | THERAPEUTIC AGENT FOR TUMOR | EISAI R&D MAN CO LTD (JP) | 2015-11-25 | — | — | EP | claimed |
| EP-2036557-B1 | ANTITUMOR AGENT FOR THYROID CANCER | EISAI R&D MAN CO LTD (JP) | 2015-10-21 | — | — | EP | claimed |
| US-9012458-B2 | Antitumor agent using compounds having kinase inhibitory effect in combination | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2015-04-21 | — | — | US | claimed |
| US-9006240-B2 | Method for assay on the effect of vascularization inhibitor | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2015-04-14 | — | — | US | claimed |
| US-8969344-B2 | Method for assay on the effect of vascularization inhibitor | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2015-03-03 | — | — | US | claimed |
| US-8962650-B2 | Therapeutic agent for tumor | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2015-02-24 | — | — | US | claimed |
| EP-2119707-B1 | COMPOSITION FOR TREATMENT OF UNDIFFERENTIATED-TYPE OF GASTRIC CANCER | EISAI R&D MAN CO LTD (JP) | 2015-01-14 | — | — | EP | claimed |
| EP-1925676-A1 | METHOD FOR ASSAY ON THE EFFECT OF VASCULARIZATION INHIBITOR | Eisai R&D Management Co., Ltd. (JP) | 2008-05-28 | — | — | EP | claimed |
| EP-1925941-A1 | METHOD FOR PREDICTION OF THE EFFICACY OF VASCULARIZATION INHIBITOR | Eisai R&D Management Co., Ltd. (JP) | 2008-05-28 | — | — | EP | claimed |
| US-7253286-B2 | Urea derivatives containing aromatic or heteroaromatic rings, useful as prophylactic or therapeutic agent for a disease for which angiogenesis inhibition is effective | EISAI CO., LTD (JP) | 2007-08-07 | — | — | US | claimed |
| EP-1797877-A1 | JOINT USE OF SULFONAMIDE BASED COMPOUND WITH ANGIOGENESIS INHIBITOR | Eisai Co., Ltd. (JP) | 2007-06-20 | — | — | EP | claimed |
| EP-1415987-B1 | NITROGENOUS AROMATIC RING COMPOUNDS AS ANTI CANCER AGENTS | EISAI R&D MAN CO LTD (JP) | 2007-02-28 | — | — | EP | claimed |
| US-20060135486-A1 | Use of sulfonamide-including compounds in combination with angiogenesis inhibitors | EISAI CO., LTD. (JP) | 2006-06-22 | — | — | US | claimed |
| EP-1604665-A1 | C-KIT KINASE INHIBITOR | Eisai Co., Ltd. (JP) | 2005-12-14 | — | — | EP | claimed |
| US-20040253205-A1 | c-Kit kinase inhibitor | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2004-12-16 | — | — | US | claimed |
| EP-1415987-A1 | NITROGENOUS AROMATIC RING COMPOUNDS | Eisai Co., Ltd. (JP) | 2004-05-06 | — | — | EP | claimed |
| US-20040053908-A1 | Urea derivatives containing aromatic or heteroaromatic rings, useful as prophylactic or therapeutic agent for a disease for which angiogenesis inhibition is effective | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2004-03-18 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040053908-A1 | Urea derivatives containing aromatic or heteroaromatic rings, useful as prophylactic or therapeutic agent for a disease for which angiogenesis inhibition is effective | VEGFA, UACA, UTS2R | KDR 22/4885PDGFRA 1572/4885RET 1681/4885 |
| US-20060135486-A1 | Use of sulfonamide-including compounds in combination with angiogenesis inhibitors | FLT4, KDR, FLT1 | KDR 2/4885PDGFRA 13/4885RET 1075/4885 |
| US-20040253205-A1 | c-Kit kinase inhibitor | KIT, MASTL, TNNI3K | KDR 368/4885PDGFRA 752/4885RET 55/4885 |
| US-20250177302-A1 | LIPOSOME COMPOSITION AND LIPOSOME-CONTAINING PHARMACEUTICAL COMPOSITION | SGMS2, DEGS1, SGMS1 | KDR 1956/4885PDGFRA 2212/4885RET 4404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.