Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 2/20 | 0.41 |
| ▸ | LIG1 | P18858 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.39 |
| ▸ | MPO | P05164 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 2/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.35 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12879068 | 0.85 | PTPN1 (0.49) | MPOGAAKDM4ESMN1; SMN2HIF1A | |
| SCHEMBL20814166 | 0.75 | MCL1 (0.47) | MCL1GAAKDM4EALDH1A1PTPN2 | |
| SCHEMBL13927042 | 0.75 | ALDH1A1 (0.47) | MCL1GAAALDH1A1 | |
| SCHEMBL13926964 | 0.75 | ALDH1A1 (0.51) | MCL1GAAALDH1A1TDP1LMNA | |
| SCHEMBL13926963 | 0.74 | ALDH1A1 (0.50) | MCL1ALDH1A1 | |
| SCHEMBL13926965 | 0.74 | ALDH1A1 (0.50) | MCL1ALDH1A1TDP1LMNA | |
| SCHEMBL220169 | 0.74 | MCL1 (0.51) | MCL1ALDH1A1PTPN2PTPN1PTPN6 | |
| SCHEMBL3809792 | 0.74 | HDAC1 (0.62) | HDAC1ALDH1A1KDM1AHDAC6HDAC7 | |
| SCHEMBL13926971 | 0.72 | HPGD (0.43) | MCL1GAAKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL13926968 | 0.72 | MEN1 (0.52) | MCL1SMN1; SMN2ALDH1A1TDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840960-A | ANTITUMOR | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1998-11-24 | — | — | US | disclosed |