Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | NMT1 | P30419 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8638976 | 0.89 | PTGS2 (0.37) | PTGS2PTGS1HTTSMN1; SMN2NPSR1 | |
| SCHEMBL8638192 | 0.87 | TAAR1 (0.42) | PTGS2PTGS1SMN1; SMN2NPSR1LMNA | |
| SCHEMBL8643560 | 0.83 | HTT (0.39) | MEN1KMT2APTGS2PTGS1HTT | |
| SCHEMBL8639075 | 0.81 | PTGS2 (0.41) | PTGS2PTGS1NPSR1LMNAMAPT | |
| SCHEMBL8688627 | 0.80 | PTGS2 (0.44) | PTGS2PTGS1SMN1; SMN2NPSR1LMNA | |
| SCHEMBL8693949 | 0.79 | PTGS1 (0.44) | MEN1KMT2APTGS2PTGS1HTT | |
| SCHEMBL8689171 | 0.78 | PTGS2 (0.41) | MEN1KMT2APTGS2PTGS1SMN1; SMN2 | |
| SCHEMBL8688468 | 0.78 | PTGS2 (0.39) | PTGS2PTGS1SMN1; SMN2NPSR1MAPT | |
| SCHEMBL8689002 | 0.78 | PTGS1 (0.55) | PTGS2PTGS1HTTSMN1; SMN2 | |
| SCHEMBL8689174 | 0.76 | ALDH1A1 (0.45) | MEN1KMT2APTGS2PTGS1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753688-A | ANTIINFLAMMATORY | TALLEY JOHN J (US) | 1998-05-19 | — | — | US | disclosed |