SCHEMBL8637602

SCHEMBL8637602

C=CCOc1cccc([O])c1-c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIG1 P18858 1/20 0.44
TSHR P16473 2/20 0.43
HPGD P15428 1/20 0.43
MAPK1 P28482 1/20 0.43
HSD17B10 Q99714 1/20 0.43
CYP3A4 P08684 1/20 0.42
CYP2A6 P11509 1/20 0.42
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA9 Q16790 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
ADRA2A P08913 1/20 0.38
ADRA2B P18089 1/20 0.38
ADRA2C P18825 1/20 0.38
MAPT P10636 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
ALDH1A1 P00352 2/20 0.38
TXNRD1 Q16881 1/20 0.38
TXNRD3 Q86VQ6 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3683087 0.81 LIG1 (0.53) LIG1TSHRHPGDMAPK1HSD17B10
SCHEMBL28538422 0.81 HPGD (0.46) LIG1TSHRHPGDMAPK1HSD17B10
SCHEMBL28547488 0.81 HPGD (0.43) LIG1TSHRHPGDMAPK1HSD17B10
SCHEMBL8637600 0.75 LIG1 (0.47) LIG1TSHRHPGDMAPK1HSD17B10
1,2-Diallyloxybenzene SCHEMBL366516 0.74 HPGD (0.60) LIG1TSHRHPGDMAPK1HSD17B10
1,2-Diallyloxybenzene SCHEMBL29768784 0.74 HPGD (0.60) LIG1TSHRHPGDMAPK1HSD17B10
SCHEMBL515196 0.74 ADRB2 (0.59) LIG1TSHRHPGDMAPK1HSD17B10
SCHEMBL9804214 0.74 TSHR (0.54) LIG1TSHRHPGDMAPK1HSD17B10
SCHEMBL4957321 0.74 MAPT (0.50) LIG1TSHRHPGDMAPK1HSD17B10
SCHEMBL20454563 0.73 HPGD (0.47) LIG1TSHRHPGDMAPK1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5747604-A CROSSLINKABLE POLYMERS FOR FILMS, POLYSTYRENE, POLYMETHYL METHACRYLATE, POLYACRYLONITRILE, POLYACRYLIC ACID AND POLYDIMETHYLSILOXANE THE PENN STATE RESEARCH FOUNDATION (US) 1998-05-05 US disclosed