Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 4/20 | 0.55 |
| ▸ | MMP3 | P08254 | 4/20 | 0.43 |
| ▸ | MMP1 | P03956 | 3/20 | 0.43 |
| ▸ | MMP9 | P14780 | 3/20 | 0.43 |
| ▸ | ACE | P12821 | 4/20 | 0.43 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CPA1 | P15085 | 2/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8641870 | 0.93 | MME (0.48) | MMEMMP3MMP1MMP9 | |
| SCHEMBL8641863 | 0.92 | MME (0.49) | MMEMMP3MMP1MMP9ACE | |
| SCHEMBL8756920 | 0.91 | REN (0.47) | MMEMMP3ACE | |
| SCHEMBL8641283 | 0.90 | MME (0.66) | MMEMMP9ACEGPR88HPGD | |
| SCHEMBL8642379 | 0.86 | MME (0.44) | MMEMMP3MMP1MMP9GPR88 | |
| SCHEMBL8637603 | 0.86 | MMP9 (0.50) | MMEMMP3MMP1MMP9 | |
| SCHEMBL8640416 | 0.86 | MME (0.53) | MMEACEHPGDCPA1ACE2 | |
| SCHEMBL8640345 | 0.86 | MME (0.53) | MMEACEHPGDCPA1ACE2 | |
| Hydrochloric Acid SCHEMBL8636625 | 0.84 | MMP9 (0.46) | MMEMMP3MMP1MMP9ACE | |
| SCHEMBL8640412 | 0.84 | REN (0.46) | MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0766694-B1 | PEPTIDE DERIVATIVES WITH METALLOPEPTIDASE INHIBITORY ACTIVITY | ZAMBON SPA (IT) | 1998-08-05 | — | — | EP | claimed |
| EP-0766694-B1 | PEPTIDE DERIVATIVES WITH METALLOPEPTIDASE INHIBITORY ACTIVITY | ZAMBON SPA (IT) | 1998-08-05 | — | — | EP | disclosed |