Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 2/20 | 0.53 |
| ▸ | ACE | P12821 | 9/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CPA1 | P15085 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | CTSG | P08311 | 1/20 | 0.38 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.38 |
| ▸ | CMA1 | P23946 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8640416 | 1.00 | MME (0.53) | MMEACEHPGDCPA1ACE2 | |
| SCHEMBL8641283 | 0.87 | MME (0.66) | MMEACEHPGDCPA1ACE2 | |
| SCHEMBL8637613 | 0.86 | MME (0.55) | MMEACEHPGDCPA1ACE2 | |
| SCHEMBL8639879 | 0.83 | ACE (0.42) | MMEACEMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8638471 | 0.83 | MMP2 (0.49) | HPGDMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8636801 | 0.83 | ALDH1A1 (0.43) | HPGDMEN1HTTKMT2A | |
| SCHEMBL10943984 | 0.82 | MME (0.49) | MMEACEHPGD | |
| SCHEMBL10942461 | 0.80 | ACE (0.46) | MMEACEMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8641870 | 0.80 | MME (0.48) | MMEKMT2A | |
| SCHEMBL7229919 | 0.79 | MME (0.58) | MMEACEHPGDMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0766694-B1 | PEPTIDE DERIVATIVES WITH METALLOPEPTIDASE INHIBITORY ACTIVITY | ZAMBON SPA (IT) | 1998-08-05 | — | — | EP | claimed |
| EP-0766694-B1 | PEPTIDE DERIVATIVES WITH METALLOPEPTIDASE INHIBITORY ACTIVITY | ZAMBON SPA (IT) | 1998-08-05 | — | — | EP | disclosed |