Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 11/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.38 |
| ▸ | F10 | P00742 | 5/20 | 0.37 |
| ▸ | F2 | P00734 | 2/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 4/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.35 |
| ▸ | PROC | P04070 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8637272 | 0.83 | CRACR2A (0.43) | PTGS2PTGS1F10F2PDPK1 | |
| SCHEMBL8981267 | 0.82 | PTGS2 (0.53) | PTGS2PTGS1PDPK1 | |
| SCHEMBL8641063 | 0.82 | CRACR2A (0.42) | PTGS2PTGS1F10F2PDPK1 | |
| SCHEMBL8639303 | 0.82 | CRACR2A (0.42) | PTGS2PTGS1F10F2PDPK1 | |
| SCHEMBL8644078 | 0.80 | PTGS2 (0.39) | PTGS2PTGS1F10F2PDPK1 | |
| SCHEMBL8637619 | 0.75 | ALOX15 (0.34) | PTGS2PTGS1 | |
| SCHEMBL8641446 | 0.74 | CRACR2A (0.40) | PTGS2PTGS1F10F2PDPK1 | |
| SCHEMBL8688891 | 0.73 | PTGES2 (0.39) | PTGS2PTGS1F10F2PDPK1 | |
| SCHEMBL8641235 | 0.72 | PTGS2 (0.64) | PTGS2PTGS1PDPK1 | |
| SCHEMBL8640768 | 0.71 | PTGS2 (0.67) | PTGS2PTGS1PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753688-A | ANTIINFLAMMATORY | TALLEY JOHN J (US) | 1998-05-19 | — | — | US | disclosed |
| US-5510496-A | ANTIINFLAMMATORY AGENTS | G.D. SEARLE & CO. (US) | 1996-04-23 | — | — | US | disclosed |