Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | ESRRA | P11474 | 2/20 | 0.46 |
| ▸ | AR | P10275 | 6/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8637194 | 0.87 | SHBG (0.46) | NPC1RAB9AMAPTPOLBCYP2C9 | |
| SCHEMBL8633319 | 0.85 | ESRRA (0.54) | NPC1RAB9AMAPTPOLBPTPN1 | |
| SCHEMBL8635974 | 0.83 | ESRRA (0.46) | ESRRAARTHRBLMNA | |
| SCHEMBL16648399 | 0.81 | ESRRA (0.49) | ESRRAARALDH1A1THRB | |
| SCHEMBL8635710 | 0.81 | LTA4H (0.54) | MAPTPTPN1ESRRAARATM | |
| SCHEMBL12806832 | 0.80 | NPC1 (0.68) | NPC1RAB9AMAPTPOLBCYP2C9 | |
| SCHEMBL8635438 | 0.79 | LTA4H (0.50) | RAB9AESRRAARL3MBTL1GAA | |
| SCHEMBL8632738 | 0.78 | LTA4H (0.57) | ESRRAARTHRB | |
| SCHEMBL8633573 | 0.78 | LTA4H (0.57) | ESRRAARATML3MBTL1GAA | |
| SCHEMBL8635775 | 0.78 | MAPT (0.45) | NPC1RAB9AMAPTPOLBCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0648729-B1 | Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound | SUMITOMO CHEMICAL CO (JP) | 1998-07-15 | — | — | EP | disclosed |
| US-5698702-A | INTERMEDIATES FOR INSECTICIDES, ACARICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-12-16 | — | — | US | disclosed |
| EP-0648729-A1 | Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1995-04-19 | — | — | EP | disclosed |