Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 4/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2167377 | 0.89 | MAOB (0.50) | ADRB2ADRB1ADRB3 | |
| SCHEMBL8635189 | 0.88 | KCNH2 (0.43) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| SCHEMBL9133931 | 0.88 | SLC2A1 (0.53) | SLC2A1MEN1LMNAKMT2A | |
| SCHEMBL8637848 | 0.88 | MAOB (0.48) | SLC2A1 | |
| SCHEMBL8638563 | 0.88 | MEN1 (0.49) | SLC2A1MEN1KMT2A | |
| SCHEMBL8636531 | 0.87 | BCHE (0.53) | SLC2A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8636522 | 0.87 | MAOB (0.48) | SLC2A1 | |
| SCHEMBL9134138 | 0.85 | ADRB2 (0.39) | SLC2A1ADRB2ADRB1ADRB3MEN1 | |
| SCHEMBL9135007 | 0.84 | BCHE (0.52) | SLC2A1 | |
| SCHEMBL8640665 | 0.82 | MAOB (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0643688-B1 | SUBSTITUTED (ARYLALKOXYBENZYL)AMINOPROPANAMIDE DERIVATIVES, THEIR PREPARATION AND USE AS ANTI-EPILEPTIC, NEUROPROTECTIVE AND ANTIDEPRESSANT AGENTS | PHARMACIA & UPJOHN SPA (IT) | 1998-07-29 | — | — | EP | disclosed |
| EP-0643688-A1 | SUBSTITUTED (ARYLALKOXYBENZYL)AMINOPROPANAMIDE DERIVATIVES, THEIR PREPARATION AND USE AS ANTI-EPILEPTIC, NEUROPROTECTIVE AND ANTIDEPRESSANT AGENTS | PHARMACIA & UPJOHN S.p.A. (IT) | 1995-03-22 | — | — | EP | disclosed |
| WO-1994022808-A1 | SUBSTITUTED (ARYLALKOXYBENZYL)AMINOPROPANAMIDE DERIVATIVES, THEIR PREPARATION AND USE AS ANTI-EPILEPTIC, NEUROPROTECTIVE AND ANTIDEPRESSANT AGENTS | FARMITALIA CARLO ERBA SRL (IT) | 1994-10-13 | — | — | WO | disclosed |