Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP14 | P50281 | 1/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8637818 | 0.88 | SLC2A1 (0.47) | MEN1KMT2ASLC2A1 | |
| SCHEMBL9133931 | 0.88 | SLC2A1 (0.53) | MEN1KMT2ABCHESLC2A1 | |
| SCHEMBL8637848 | 0.88 | MAOB (0.48) | BCHESLC2A1 | |
| SCHEMBL8636531 | 0.87 | BCHE (0.53) | MEN1KMT2ABCHESIGMAR1SLC2A1 | |
| Hydrochloric Acid SCHEMBL8636522 | 0.87 | MAOB (0.48) | BCHESLC2A1 | |
| SCHEMBL9135007 | 0.84 | BCHE (0.52) | BCHESIGMAR1SLC2A1FFAR1 | |
| SCHEMBL8640665 | 0.82 | MAOB (0.49) | BCHEPPARG | |
| SCHEMBL8638577 | 0.82 | BCHE (0.43) | MEN1KMT2ABCHESLC2A1FFAR1 | |
| SCHEMBL8635189 | 0.82 | KCNH2 (0.43) | MEN1KMT2ABCHE | |
| SCHEMBL8636498 | 0.82 | FAAH (0.42) | BCHEALDH1A1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0643688-B1 | SUBSTITUTED (ARYLALKOXYBENZYL)AMINOPROPANAMIDE DERIVATIVES, THEIR PREPARATION AND USE AS ANTI-EPILEPTIC, NEUROPROTECTIVE AND ANTIDEPRESSANT AGENTS | PHARMACIA & UPJOHN SPA (IT) | 1998-07-29 | — | — | EP | disclosed |
| US-5446066-A | Antiepileptic, antidepressants, antispastic agent | FARMITALIA CARLO ERBA S.R.L. (IT) | 1995-08-29 | — | — | US | disclosed |