Sugi Predict

Sugi Predict / Compounds / SCHEMBL6400882

SCHEMBL6400882

SCHEMBL6400882

CCCC[PH](=O)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ CES2 O00748 3/20 0.37
▸ CES1 P23141 3/20 0.37
▸ SMN1; SMN2 Q16637 1/20 0.37
▸ TDP1 Q9NUW8 1/20 0.36
▸ TSHR P16473 1/20 0.36
▸ PCSK9 Q8NBP7 1/20 0.35
▸ LTA4H P09960 1/20 0.35
▸ EPHX2 P34913 1/20 0.35
▸ PKM P14618 1/20 0.35
▸ PTGS2 P35354 1/20 0.34
▸ NAAA Q02083 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5138546 0.94 CES2 (0.39) CES2CES1SMN1; SMN2LTA4HEPHX2
SCHEMBL8637868 0.92 CES2 (0.41) CES2CES1EPHX2PKMNAAA
SCHEMBL27519996 0.92 CES2 (0.41) CES2CES1EPHX2PKMNAAA
SCHEMBL27520002 0.92 CES2 (0.41) CES2CES1EPHX2PKMNAAA
SCHEMBL27411391 0.92 CES2 (0.41) CES2CES1EPHX2PKMNAAA
SCHEMBL9347727 0.92 CES2 (0.41) CES2CES1EPHX2PKMNAAA
SCHEMBL29184852 0.90 CES2 (0.40) CES2CES1EPHX2PKMNAAA
SCHEMBL5572993 0.86 TP53 (0.35) CES2CES1SMN1; SMN2TSHR
SCHEMBL4867131 0.86 MAOB (0.31) TDP1
SCHEMBL27731628 0.79 TSHR (0.44) TDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119075972-A MoO reinforced by radio frequency plasma technology3/g-C3N4Catalyst and application of catalyst in phosphonation reaction 中国人民解放军军事科学院防化研究院 2024-12-06 — — CN claimed
CN-111606945-B Preparation method of compound containing P-O bond or P-S bond 烟台大学 2023-06-20 — — CN claimed
CN-114181250-A Alkenyl phosphine compound and preparation method thereof 中国石油化工股份有限公司 2022-03-15 — — CN claimed
CN-113583042-A Preparation method of phosphoryl fluoride compound 烟台大学 2021-11-02 — — CN claimed
CN-119075972-A MoO reinforced by radio frequency plasma technology3/g-C3N4Catalyst and application of catalyst in phosphonation reaction 中国人民解放军军事科学院防化研究院 2024-12-06 — — CN disclosed
CN-116804029-B Fluorination method of secondary phosphine oxide 浙江工业大学 2024-08-27 — — CN disclosed
CN-114805430-B Preparation method of selenophosphide and thiophosphoride 烟台大学 2024-02-13 — — CN disclosed
CN-114560889-B Asymmetric phospho-pyridine triazine derivative and synthetic method thereof 浙江大学 2023-11-24 — — CN disclosed
CN-116804029-A Fluorination method of secondary phosphine oxide 浙江工业大学 2023-09-26 — — CN disclosed
CN-113583042-B Preparation method of phosphoryl fluoride compound 烟台大学 2023-08-29 — — CN disclosed
US-20230212204-A1 REAGENTS AND THEIR USE FOR MODULAR ENANTIODIVERGENT SYNTHESIS OF C-P BONDS THE SCRIPPS RESEARCH INSTITUTE 2023-07-06 — — US disclosed
CN-111606945-B Preparation method of compound containing P-O bond or P-S bond 烟台大学 2023-06-20 — — CN disclosed
US-20130131366-A1 Metal Complex Compound and Process for Producing Amides Utilizing the Metal Complex Compound NATIONAL UNIVERSITY CORPORATION OKAYAMA UNIVERSITY (JP) 2013-05-23 — — US disclosed
US-20100174079-A1 PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE PHOSPHOROUS COMPOUND NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE TECHNOLOGY (JP) 2010-07-08 — — US disclosed
US-7196228-B2 Multimer forms of mono-and bis-acylphosphine oxides CIBA SPECIALTY CHEMICALS CORPORATION (US) 2007-03-27 — — US disclosed
US-6955851-B2 Hydroxyaryl phosphine oxides, glycidyl ethers and epoxy compositions, composites and laminates derived therefrom PABU SERVICES, INC. (US) 2005-10-18 — — US disclosed
CN-1200943-C Organometallic acyl-aryl phosphine CIBA SC HOLDING AG (CH) 2005-05-11 — — CN disclosed
CN-1308081-A Organometallic acyl-aryl phosphine CIBA SC HOLDING AG (CH) 2001-08-15 — — CN disclosed
EP-1080381-A1 HIGH REFRACTIVE INDEX OPHTHALMIC DEVICE MATERIALS PREPARED USING A POST-POLYMERIZATION CROSS-LINKING METHOD ALCON LABORATORIES, INC. (US) 2001-03-07 — — EP disclosed
WO-1999053348-A1 HIGH REFRACTIVE INDEX OPHTHALMIC DEVICE MATERIALS PREPARED USING A POST-POLYMERIZATION CROSS-LINKING METHOD ALCON LABORATORIES, INC. (US) 1999-10-21 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130131366-A1 Metal Complex Compound and Process for Producing Amides Utilizing the Metal Complex Compound AP2M1, ASH2L, AP2A1 CES2 3764/4885CES1 3342/4885SMN1; SMN2 1821/4885
US-20230212204-A1 REAGENTS AND THEIR USE FOR MODULAR ENANTIODIVERGENT SYNTHESIS OF C-P BONDS PNKP, POLL, RNGTT CES2 1531/4885CES1 2055/4885SMN1; SMN2 3210/4885
US-20100174079-A1 PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE PHOSPHOROUS COMPOUND AGL, RPS4X, MRPL9 CES2 4375/4885CES1 3871/4885SMN1; SMN2 3107/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.